Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1’s pro-metastatic functions in esophageal cancer

Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1's pro-metastatic functions in esophageal cancer

Background: Esophageal cancer is one of the most common cancer worldwide with poor prognosis and high mortality. SNAI1 transcription factors, coding Snail1, it is important for the development of esophageal cancer metastasis while microRNA (miRNA) -203 has been shown to function as inhibitors of metastasis in the EC. The EC Snail1 protein is stabilized in part by deubiquitinating enzymes USP26; However, how USP26 set is not fully known.


Methods: Expression SNAI1 and USP26 messenger RNA (mRNA) and miR-203 performed on datasets in The Cancer Genome Atlas and Gene Expression Omnibus, respectively. Snail1 and USP26 protein expression and miR-203 are determined in normal esophageal cell lines HET-1A and Kyse150 EC cell lines and TE-1 using western blot and quantitative polymerase chain reaction, respectively. TargetScan used for in situ predicted miR-203 targets and in vitro assays using a heterologous reporter wild-type and miR-203 mutant seeds from the 3 ‘translated region (UTR) of USP26 is used to investigate whether USP26 is a target of miR-203.

The effect of the increase in miR-203 using MIR203A / 5P mimic the USP26 and Snail1 in HET-1A, Kyse150 and TE-1 cell line is done by using western blot analysis of the stability of protein-based and cycloheximide. Modulating effect of miR-203 in Kyse150 and TE-1 cell lines in vitro pro-metastatic effect was analyzed by test invasion, early test wound healing, and chemosensitivity to 5-fluorouracil (5-FU). In vivo lung metastasis assay was used to study the effect of modulation of miR-203 in cells Kyse150.

 Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1's pro-metastatic functions in esophageal cancer
Targeting deubiquitinating enzyme USP26 by microRNA-203 regulates Snail1’s pro-metastatic functions in esophageal cancer


Results: The mRNA SNAI1 and HSA / MIR203 higher and lower, respectively, in patients with EC compared with tumor-adjacent normal tissue. No changes USP26 mRNA expression was observed in this dataset. MIR / 203 expression was downregulated while the protein expression of both Snail1 and USP26 higher EC Kyse150 cell lines and TE-1 compared to normal esophageal cell lines HET-1A. USP26 is estimated as a potential target of miR-203 by TargetScan Release 2.0. Reporter tests confirmed USP26 as a target of miR-203 in the EC cell line.

Transfection of cell lines with MIR203 imitating EC decreased USP26 protein expression and protein stability Snail1 showed miR-203’s ability to regulate protein levels Snail1 through USP26. exogenous increase in miR-203 in cell lines significantly inhibited Snail EC-1 mediated in vitro function of pro-metastatic invasion, wound healing, and increased chemosensitivity to 5-FU. Finally, overexpression of miR-203 inhibited in vivo lung metastasis Kyse150 cells, which reversed following overexpression of USP26, suggesting a direct role of the regulation of miR-203-mediated metastasis USP26 in the development of EC.


Conclusion: Cumulatively, these results establish an important mechanism whereby a decrease in the expression of miR-203 potentiates the development of metastases in the EC through USP26-mediated stabilization Snail1. Therefore, miR-203 can serve as a biomarker of metastasis in EC and is a potential target for therapeutic intervention in the EC.

Elastase, Porcine Pancreas

P1276-250
EUR 218

Chymotrypsin, Human Pancreas

CHYT15-N-100 100 ug
EUR 286

Trypsin, Human Pancreas

TRYP15-N-50 50 ug
EUR 225

cDNA from Lupus: Pancreas

C1236188Lup 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Alpha-Amylase, Human Pancreas

P1545-100 100 units
EUR 348

Human Pancreas Tissue Lysate

30R-AP030 150 ug
EUR 219
Description: Fresh tissue lysate isolated from human pancreas

Alpha-Amylase, Human Pancreas

P1454-100
EUR 370

Human Pancreas Chymotrypsin Protein

abx060937-100ug 100 ug
EUR 481

Insulin from bovine pancreas

abx082234-25mg 25 mg
EUR 217

Elastase from Porcine Pancreas

30047 1 mg
EUR 99.3
Description: Elastase from Porcine Pancreas

CK PANCREAS 25 EA*

43031-2 25 EA
EUR 295.55

Pig PANCREAS 10 EA*

59431-2 10 EA
EUR 318.39

Human Pancreas Tumor lysate

HTL-1334 1 mg
EUR 773

cDNA from Liver Cirrhosis: Pancreas

C1236188Lcs 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Frozen Tissue Section - Lupus: Pancreas

T1236188Lup 5 slides
EUR 474
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Lupus: Pancreas

T2236188Lup 5 slides
EUR 249
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Recombinant Phospholipase A2, Pancreas (pPLA2)

4-RPD826Hu01
  • EUR 449.44
  • EUR 223.00
  • EUR 1410.40
  • EUR 536.80
  • EUR 973.60
  • EUR 364.00
  • EUR 3376.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Phospholipase A2, Pancreas expressed in: E.coli

Total Protein from Lupus: Pancreas

P1236188Lup 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA from Lupus: Pancreas

R1236188Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Phospholipase A2, Pancreas (pPLA2) Antibody

20-abx128460
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Phospholipase A2, Pancreas (pPLA2) Antibody

20-abx178008
  • EUR 1414.00
  • EUR 662.00
  • 1 mg
  • 200 ug

Phospholipase A2, Pancreas (pPLA2) Antibody

20-abx174050
  • EUR 982.00
  • EUR 495.00
  • 1 mg
  • 200 ug

Pig (Pancreas) alpha Amylase Enzyme

abx070001-25kU 25 kU
EUR 648

Human (Pancreas) Amylase alpha Enzyme

abx070003-100Units 100 Units
EUR 453

Ribonuclease A from bovine pancreas

abx082524-25mg 25 mg
EUR 189

Rabbit PANCREAS Y 25 EA*

41231-2 25 EA
EUR 341.23

Rabbit PANCREAS MATURE 25 EA*

41331-2 25 EA
EUR 341.23

CK PANCREAS POWDER LYOPH 1g*

43032-0 1g
EUR 122.64

CK PANCREAS POWDER LYOPH 10g*

43032-1 10g
EUR 333.61

CK PANCREAS POWDER LYOPH 100g*

43032-2 100g
EUR 2484.69

Pancreas Duodenum Homeobox-1 Antibody

20-abx137204
  • EUR 453.00
  • EUR 230.00
  • EUR 328.00
  • 100 ul
  • 10 ul
  • 50 ul

Mouse Pancreas, Peptide Aptamer, Biotinylated

AP-322-B 1 mg Ask for price

Mouse Pancreas, Peptide Aptamer, unlabeled

AP-322-U 5 mg Ask for price

Mouse Pancreas Whole tissue lysate

MAL-1414 1 mg
EUR 524

Rat Pancreas Whole tissue lysate

RAL-1469 1 mg
EUR 524

cDNA from Human Tumor Tissue: Pancreas

C1235188-10 10 reactions
EUR 282
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Human Diabetic Tissue: Pancreas

C1236188Dia 40 reactions
EUR 668
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Frozen Tissue Section - Human Tumor: Pancreas

T1235188 5 slides
EUR 338
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Pancreas Tumor

T2235188 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Liver Cirrhosis: Pancreas

T2236188Lcs 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Membrane Protein from Diabetic Disease: Pancreas

P3236188Dia 0.1 mg
EUR 408
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Liver Cirrhosis: Pancreas

P3236188Lcs 0.1 mg
EUR 408
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Liver Cirrhosis: Pancreas

P1236188Lcs 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA from Diabetic Disease: Pancreas

R1236188Dia-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Liver Cirrhosis: Pancreas

R1236188Lcs-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Mouse Pancreas PrimaCell2: Normal Pancreatic Islets

2-82081 1 Kit Ask for price

Rat Pancreas PrimaCell: Normal Pancreatic Islets

2-82578 1 Kit Ask for price

Pig Phospholipase A2, Pancreas (pPLA2) Protein

20-abx654732
  • EUR 648.00
  • EUR 272.00
  • EUR 1998.00
  • EUR 773.00
  • EUR 467.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Phospholipase A2, Pancreas (pPLA2) Protein

20-abx166479
  • EUR 634.00
  • EUR 272.00
  • EUR 1901.00
  • EUR 746.00
  • EUR 453.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Pancreas Dissociation System 3 (Duct), Mouse

4-20373 ea Ask for price

Pancreas Dissociation System 8 (Duct), Rat

4-20378 ea Ask for price

Mouse Pancreas OptiTDS2: Tissue Dissociation System

4-28195 1 Kit Ask for price

Rat Pancreas OptiTDS: Tissue Dissociation System

4-28285 1 Kit Ask for price

Salmon pancreas disease virus PCR kit

PCR-V263-48R 50T
EUR 823

Salmon pancreas disease virus PCR kit

PCR-V263-96R 100T
EUR 1113

Mouse Pancreas, Peptide Aptamer, FITC labelled

AP-322-F 1 mg Ask for price

Deoxyribonuclease (1000 U/g), Bovine Pancreas

DNS-01 1 g
EUR 651

Monkey (Cynomolgus) cDNA Normal Tissue: Pancreas

MC34-188 10 rxn
EUR 415

MicroRNA Isolation Kit

KS341025 1 kit
EUR 256
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

cDNA from Human Adult Normal Tissue: Pancreas

C1234188 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Rhesus) Normal Tissue: Pancreas

C1534188 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Cynomolgus) Normal Tissue: Pancreas

C1534188-Cy 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Immortalized Mouse Pancreas Epithelial Cells-Conditionally (IMPE)

T0156 1x106 cells / 1.0 ml Ask for price

Frozen Tissue Section - Human Adult Normal: Pancreas

T1234188 5 slides
EUR 349
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Frozen Tissue Section - Human Diabetic Tissue: Pancreas

T1236188Dia 5 slides
EUR 465
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Adult Normal: Pancreas

T2234188 5 slides
EUR 211
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Pancreas Tumor: Adenocarcinoma

T2235188-1 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Diabetic Tissue: Pancreas

T2236188Dia 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

FFPE Genomic DNA - Human Tumor Tissue: Pancreas

D2235188 2 ug
EUR 821
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Phospholipase A2, Pancreas (pPLA2) Polyclonal Antibody (Human)

4-PAD826Hu01
  • EUR 247.00
  • EUR 2510.00
  • EUR 625.00
  • EUR 310.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Phospholipase A2, Pancreas (pPLA2)

Pig Phospholipase A2, Pancreas (pPLA2) ELISA Kit

SED826Po-10x96wellstestplate 10x96-wells test plate
EUR 5647.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Phospholipase A2, Pancreas (pPLA2) in serum, plasma, tissue homogenates and other biological fluids.

Pig Phospholipase A2, Pancreas (pPLA2) ELISA Kit

SED826Po-1x48wellstestplate 1x48-wells test plate
EUR 552.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Phospholipase A2, Pancreas (pPLA2) in serum, plasma, tissue homogenates and other biological fluids.

Pig Phospholipase A2, Pancreas (pPLA2) ELISA Kit

SED826Po-1x96wellstestplate 1x96-wells test plate
EUR 746.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Phospholipase A2, Pancreas (pPLA2) in serum, plasma, tissue homogenates and other biological fluids.

Pig Phospholipase A2, Pancreas (pPLA2) ELISA Kit

SED826Po-5x96wellstestplate 5x96-wells test plate
EUR 3060.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Pig Phospholipase A2, Pancreas (pPLA2) in serum, plasma, tissue homogenates and other biological fluids.

Pig Phospholipase A2, Pancreas (pPLA2) ELISA Kit

4-SED826Po
  • EUR 5698.00
  • EUR 3011.00
  • EUR 747.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Pig Phospholipase A2, Pancreas (pPLA2) in samples from Serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Recombinant Pancreas Specific Transcription Factor 1a (PTF1a)

4-RPC738Hu01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Pancreas Specific Transcription Factor 1a expressed in: E.coli

Recombinant Pancreas Specific Transcription Factor 1a (PTF1a)

4-RPC738Hu02
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Pancreas Specific Transcription Factor 1a expressed in: E.coli

Recombinant Pancreas Specific Transcription Factor 1a (PTF1a)

4-RPC738Hu03
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Pancreas Specific Transcription Factor 1a expressed in: E.coli

Membrane Protein from Human Tumor Tissue: Pancreas

P3235188 0.1 mg
EUR 633
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Tumor Tissue: Pancreas

P1235188 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Diabetic Tissue: Pancreas

P1236188Dia 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Mouse Normal Tissue: Pancreas

P1334188 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA from Mouse Normal Tissue: Pancreas

R1334188-50 50 ug
EUR 341
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Pancreas

R1434188-50 50 ug
EUR 296
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Human Phospholipase A2, Pancreas (pPLA2)ELISA kit

201-12-2531 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx126342
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx127002
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Mouse Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-82102 1 Kit Ask for price

Rat Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-82597 1 Kit Ask for price

Human Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-96123 1 Kit Ask for price

Pancreas Specific Transcription Factor 1a (PTF1A) Antibody

20-abx318806
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Phospholipase A2, Pancreas (pPLA2) ELISA Kit

abx570720-96tests 96 tests
EUR 786

Pig Phospholipase A2, Pancreas (pPLA2) CLIA Kit

20-abx494402
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Pancreas Specific Transcription Factor 1a (PTF1A) Antibody

abx430380-200ul 200 ul
EUR 384

Pancreas Specific Transcription Factor 1a (Ptf1a) Antibody

abx433198-200ul 200 ul
EUR 286

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx241830
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx242867
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx213983
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Pancreas Specific Transcription Factor 1a (PTF1a) Antibody

20-abx173943
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Pig Phospholipase A2, Pancreas (pPLA2) ELISA Kit

20-abx154993
  • EUR 7911.00
  • EUR 4215.00
  • EUR 973.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Pancreas/duodenum homeobox protein 1 (PDX1) Antibody

20-abx327762
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

20-abx002213
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Pancreas Specific Transcription Factor 1a (PTF1a) Antibody

20-abx104250
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Pancreas Specific Transcription Factor 1a (PTF1a) Antibody

20-abx104973
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Phospholipase A2, Pancreas (pPLA2) ELISA Kit

20-abx052755
  • EUR 7378.00
  • EUR 3933.00
  • EUR 911.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Pancreas OptiTDS 2: Tissue Dissociation System

4-28308 1 Kit Ask for price

Human Pancreas OptiTDS 2: Tissue Dissociation System

4-28316 1 Kit Ask for price

Rat Pancreas OptiTDS 2: Tissue Dissociation System

4-28324 1 Kit Ask for price

Pancreas Specific Transcription Factor 1a (Ptf1a) Antibody

abx031635-400ul 400 ul
EUR 523

Pancreas Specific Transcription Factor 1a (Ptf1a) Antibody

abx031635-80l 80 µl
EUR 286

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx033651-400ul 400 ul
EUR 523

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx033651-80l 80 µl
EUR 286

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015963-100ug 100 ug
EUR 411

Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody

abx015964-100ug 100 ug
EUR 411

Pancreas Specific Transcription Factor 1a (PTF1A) Antibody

abx027663-400ul 400 ul
EUR 523

Pancreas Specific Transcription Factor 1a (PTF1A) Antibody

abx027663-80l 80 µl
EUR 286

Porcine Phospholipase A2, Pancreas (pPLA2) ELISA Kit

DLR-pPLA2-p-48T 48T
EUR 592
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Phospholipase A2, Pancreas (pPLA2) in samples from serum, plasma, tissue homogenates or other biological fluids.

Porcine Phospholipase A2, Pancreas (pPLA2) ELISA Kit

DLR-pPLA2-p-96T 96T
EUR 777
Description: A sandwich quantitative ELISA assay kit for detection of Porcine Phospholipase A2, Pancreas (pPLA2) in samples from serum, plasma, tissue homogenates or other biological fluids.

Salmon pancreas disease virus RT PCR kit

RTq-V263-100R 100T
EUR 1311

Salmon pancreas disease virus RT PCR kit

RTq-V263-150R 150T
EUR 1787

Salmon pancreas disease virus RT PCR kit

RTq-V263-50R 50T
EUR 963

Cancer of the pancreas, 102 cases (1.5mm)

PAC1021 1
EUR 295
Description: Pancreatic cancer tissue array contains 96 cases of pancreatic cancers and 6 cases of normal and non-malignant pancreatic tissues with grading and TNM staging data.

Porcine Phospholipase A2, Pancreas (pPLA2) ELISA Kit

RD-pPLA2-p-48Tests 48 Tests
EUR 606

Porcine Phospholipase A2, Pancreas (pPLA2) ELISA Kit

RD-pPLA2-p-96Tests 96 Tests
EUR 844

Porcine Phospholipase A2, Pancreas (pPLA2) ELISA Kit

RDR-pPLA2-p-48Tests 48 Tests
EUR 633

Porcine Phospholipase A2, Pancreas (pPLA2) ELISA Kit

RDR-pPLA2-p-96Tests 96 Tests
EUR 884

Cholesterol esterase (35 U/mg), Porcine Pancreas

CES-02 50000 U
EUR 5462

Monkey (Rhesus) Normal Pancreas Whole tissue lysate

MRL-1310 1 mg
EUR 524

Bovine pancreas Insulin (~30 USP U/mg)

INSL15-N-10 10 mg
EUR 408

Monkey (Cyno.) Normal Pancreas Whole tissue lysate

MCL-1198 1 mg
EUR 524

Human Adult Pancreas (Normal) Whole tissue lysate

HAL-1307 1 mg
EUR 524

Rat Phospholipase A2(Pancreas(pPLA2)ELISA kit

QY-E10541 96T
EUR 400

Mouse Phospholipase A2(Pancreas(pPLA2)ELISA kit

QY-E21174 96T
EUR 361

Human Phospholipase A2, Pancreas(pPLA2)ELISA Kit

QY-E00482 96T
EUR 361

Ribonuclease (70 U/mg material), Bovine pancreas

RNU-01 500 mg
EUR 347

Ribonuclease (90 U/mg material), Bovine pancreas

RNU-02 500 mg
EUR 469

Cancer MicroRNA qPCR Array

RA610A-1 10 profiles
EUR 1172

Human Pancreas Specific Transcription Factor 1a ELISA kit

E01P0154-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Pancreas Specific Transcription Factor 1a ELISA kit

E01P0154-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Pancreas Specific Transcription Factor 1a ELISA kit

E01P0154-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Pancreas Specific Transcription Factor 1a ELISA kit

E03P0154-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Pancreas Specific Transcription Factor 1a ELISA kit

E03P0154-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Pancreas Specific Transcription Factor 1a ELISA kit

E03P0154-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Pancreas Specific Transcription Factor 1a ELISA kit

E02P0154-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Pancreas Specific Transcription Factor 1a ELISA kit

E02P0154-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Pancreas Specific Transcription Factor 1a ELISA kit

E02P0154-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

FFPE Genomic DNA - Human Adult Normal Tissue: Pancreas

D2234188 2 ug
EUR 599
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Phospholipase A2, Pancreas (pPLA2) Polyclonal Antibody (Human), APC

4-PAD826Hu01-APC
  • EUR 345.00
  • EUR 3275.00
  • EUR 912.00
  • EUR 440.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Phospholipase A2, Pancreas (pPLA2). This antibody is labeled with APC.

Phospholipase A2, Pancreas (pPLA2) Polyclonal Antibody (Human), Biotinylated

4-PAD826Hu01-Biotin
  • EUR 311.00
  • EUR 2460.00
  • EUR 727.00
  • EUR 381.00
  • EUR 219.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Phospholipase A2, Pancreas (pPLA2). This antibody is labeled with Biotin.

Phospholipase A2, Pancreas (pPLA2) Polyclonal Antibody (Human), Cy3

4-PAD826Hu01-Cy3
  • EUR 419.00
  • EUR 4325.00
  • EUR 1175.00
  • EUR 545.00
  • EUR 251.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Phospholipase A2, Pancreas (pPLA2). This antibody is labeled with Cy3.

Phospholipase A2, Pancreas (pPLA2) Polyclonal Antibody (Human), FITC

4-PAD826Hu01-FITC
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Phospholipase A2, Pancreas (pPLA2). This antibody is labeled with FITC.

Phospholipase A2, Pancreas (pPLA2) Polyclonal Antibody (Human), HRP

4-PAD826Hu01-HRP
  • EUR 316.00
  • EUR 2855.00
  • EUR 807.00
  • EUR 398.00
  • EUR 206.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Phospholipase A2, Pancreas (pPLA2). This antibody is labeled with HRP.

Phospholipase A2, Pancreas (pPLA2) Polyclonal Antibody (Human), PE

4-PAD826Hu01-PE
  • EUR 296.00
  • EUR 2640.00
  • EUR 750.00
  • EUR 372.00
  • EUR 195.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Phospholipase A2, Pancreas (pPLA2). This antibody is labeled with PE.

Total Protein from Human Adult Normal Tissue: Pancreas

P1234188 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Membrane Protein from Human Adult Normal Tissue: Pancreas

P3234188 0.1 mg
EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Goat Pancreas Specific Transcription Factor 1a ELISA kit

E06P0154-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Pancreas Specific Transcription Factor 1a ELISA kit

E06P0154-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Pancreas Specific Transcription Factor 1a ELISA kit

E06P0154-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Pancreas Specific Transcription Factor 1a ELISA kit

E07P0154-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Pancreas Specific Transcription Factor 1a ELISA kit

E07P0154-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Pancreas Specific Transcription Factor 1a ELISA kit

E07P0154-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Pancreas Specific Transcription Factor 1a ELISA kit

E04P0154-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Pancreas Specific Transcription Factor 1a ELISA kit

E04P0154-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Pancreas Specific Transcription Factor 1a ELISA kit

E04P0154-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Pancreas Specific Transcription Factor 1a ELISA kit

E09P0154-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Pancreas Specific Transcription Factor 1a ELISA kit

E09P0154-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Pancreas Specific Transcription Factor 1a ELISA kit

E09P0154-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Pancreas Specific Transcription Factor 1a in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Total RNA from Human Adult Normal Tissue: Pancreas

R1234188-50 50 ug
EUR 178
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Monkey (Rhesus) Normal Tissue: Pancreas

R1534188-50 50 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Monkey (Cynomolgus) Normal Tissue: Pancreas

R1534188-Cy 50 ug
EUR 194
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Pancreas Specific Transcription Factor 1a (PTF1A) Antibody (HRP)

20-abx317159
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Pancreas Specific Transcription Factor 1a (PTF1A) Antibody (FITC)

20-abx317160
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Pancreas Specific Transcription Factor 1a (PTF1A) Antibody (Biotin)

20-abx317161
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Pancreas Specific Transcription Factor 1a (PTF1a) Protein

20-abx652202
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Pancreas Specific Transcription Factor 1a (PTF1a) Protein

20-abx654650
  • EUR 885.00
  • EUR 328.00
  • EUR 2834.00
  • EUR 1052.00
  • EUR 606.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Pancreas Specific Transcription Factor 1a (PTF1a) Protein

20-abx167159
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Pancreas Specific Transcription Factor 1a (PTF1a) Antibody (Biotin)

20-abx272293
  • EUR 453.00
  • EUR 244.00
  • EUR 1316.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Pancreas Specific Transcription Factor 1a (PTF1a) Protein

20-abx068415
  • EUR 732.00
  • EUR 286.00
  • EUR 2305.00
  • EUR 885.00
  • EUR 523.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Pancreas Dissociation System 4 (Islets), Mouse and Rat

4-20374 ea Ask for price

Pancreas Dissociation System 5 (Acinar, mouse parotid), Mouse

4-20375 ea Ask for price

Pancreas Dissociation System 6 (Acinar, rat parotid), Rat

4-20376 ea Ask for price

Pancreas Dissociation System 9 (Epithelial), Mouse and Rat

4-20379 ea Ask for price

Mouse FibrOut 5, for adrenal, kidney, pancreas, pituitary

4-20509 1 ml Ask for price

Mouse FibrOut 5, for adrenal, kidney, pancreas, pituitary

4-20510 5 x 1 ml Ask for price

Rat FibrOut 5, for adrenal, kidney, pancreas, pituitary

4-20535 1 ml Ask for price

Rat FibrOut 5, for adrenal, kidney, pancreas, pituitary

4-20536 5 x 1 ml Ask for price

Human FibrOut 5, for adrenal, kidney, pancreas, pituitary

4-21554 1 ml Ask for price

adverse cardiac fibrosis is involved in cardiac remodeling and heart failure, which is a major cause of heart function deteriorated. accumulative evidence has been explained that microRNAs (miRNAs) play an important role in the pathogenesis of cardiac fibrosis. However, the exact molecular mechanisms underlying the miR-144 in cardiac fibrosis is still unknown. In this study, transverse aortic constriction (TAC) and a rat model of angiotensin II (Ang II) induced cardiac fibroblasts (CF) was created to investigate the expression level of miR-144.

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