Identification of a miRNA based model to detect prognostic subgroups in patients with aggressive B-cell lymphoma

To distinguish prognostic subgroups patients with aggressive B cell lymphoma, we analyzed 800 MIRNAS’s expression with Nanostring NCounter Micna Mirna Test on cohort 228 FFPE samples of patients registered in the Ricover-60 trial and megachoep. We identify significant Mirna signatures for the overall survival (OS) (OS) and progressive free survival (PFS) with linear cox regression punished by Laso. The level of high expression of the MIR-130A-3P and MIR-423-5P shows a better prognosis, while the high level of MIR-374B-5P, MIR-590-5P, MIR-186-5P, and MIR-106B-5P-5P increases Patients’ risk level for OS.

Regarding the PFS high expression MIR-365A-5P In addition to two other MIRNAS increases the prognosis and high level of MIR374A-5P, MIR-106B-5P, and MIR-590-5P, connected with an increased risk and poor prognosis. We identified the signature of Mirna to divide patients into two different risk groups. This prognostic model can be used in risk stratification in clinical trials in the future and helps make personalized therapeutic decisions.

Comparative analysis of transcript profile, proteome, and mirna cupffer cells and monocytes

The macrophage population in most mammalian organs consists of different origin cells. The macrophage of the population comes from the erythromiseloid precursor of the wall of the egg yolk bag; Maintenance of the amount of macrophages in the postnatal ontogenesis is practically independent of the hematopoiesis bone marrow. The largest population of the population of embryonic population is found in the central nervous system (Mikroglia) and the liver (Cell Cupffer). Conversely, dermis and mucous membranes become largely colonized by monocytes of bone marrow derivatives which show clear and phenotical plasticity.

In this study, we compare cupffer cells and monocytes using immunofenotype, gene expression profiles, proteome, and microrna collections. The observed difference does not consider the macrophage of the residents’ hearts as pure m2 macrophages or the situation owned by a monocyte has a pure M1 feature. Monocytes show signs of high plasticity and sensitivity to the pattern of molecules related to pathogens (for example, high transcription rates for <i> TLR 2 </ i>, <i> 4 </ i>, <i> 7 </ i>, and <i> 8 </ i>). Conversely, the macrophage of the Heart of the population is clearly involved in the regulations of certain organ functions (nitrogen metabolism, a complementary system protein synthesis).

PMDNE: Prediction of the Mirna-Disease Association based on network embedding and network similarity analysis

Prediction of success from the Mirna-Disease Association is nontrivial for the diagnosis and prognosis of genetic diseases. There are many methods for predicting mirna and disease, but many biological data and complex, and they are often in network form. Ways to accurately use MIRNA features and biological tissue related to diseases to predict unknown associations always become a challenge. Here, we propose PMDNE, a method based on network embedding and network similarity analysis, to predict Mirna’s associations.

At PMDNE, the structure of bipartite graphics network is improved, and the generator runs randomly designed. For embedded vectors, 128 dimensions are used, and predictive accuracy increases significantly. Compared to other network embedding methods, PMDNE is comparable and competitive with the method of art conditions. The method we can solve features extraction features, reduce the dimensions of features, and increase the efficiency of predictions of mirna-disease associations. This method can also be extended to other areas for biomedical tissue predictions.

Effect of lifestyle factors on mirna expression and signal paths: reviews

The term ‘lifestyle’ includes various factors that contribute to maintenance of good health status. Increased evidence shows that lifestyle factors can affect epigenetic mechanisms, such as MIRNAS’s expression. MIRNA dysregulation can modify gene expression and molecular pathways that can cause functional changes. This review summarizes human studies that highlights that diet, physical activity, smoking consumption and alcohol can affect the Mirna engine and some biological functions.

Most Mirnas are involved in molecular lines that affect inflammation, cell cycle regulations and carcinogenesis produce onset or the development of pathological conditions. Investigating this interaction will be very important to understand the etiology of the pathological process, the potential for new care strategies and to prevent disease.

From the Mirna target network to the Mirna function: MIR-375 can regulate apoptosis and dynamics of actin in the heart muscle through the path that depends on RHO-GTPASES

Micrornas (MIRNAS) is a short ribonucleic acid molecule (RNA), without code, which is involved in the main biological process regulations, such as apoptosis or proliferation and cell differentiation, through specific interactions of sequences with the MRNAS target. In this study, we propose workflows to predict the MIRNA function by analyzing their target gene network structure. This workflow is applied to study the functional role of the MIR-375 in the heart of the muscle (myocardium), because Mirna previously proved to be associated with heart disease, and the data on its functions in myocardium was largely unclear.

Hygromycin B

40810000-2 100 mg
EUR 35.69

Hygromycin B

40810000-3 250 mg
EUR 53.99

Hygromycin B

40810000-4 1 g
EUR 67.81

Hygromycin B

40810000-5 5 g
EUR 255.31

Hygromycin B

40810000-8 25 g
EUR 905.02

Hygromycin B

40810000-9 10 g
EUR 493.23

Hygromycin B

abx184120-1g 1 g
EUR 360

Hygromycin B

AT190 1mg
EUR 1336.8

Hygromycin B

A2515-200 200 mg
EUR 40
Description: Suitable for mammalian cell selection

Hygromycin B

A2515-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Hygromycin B is a selective antibiotic.Antibiotics are a type of antimicrobial used in the treatment and prevention of bacterial infection.Hygromycin B is an antibiotic that is effective on most bacteria, fungi and higher eukaryotes.

Hygromycin B

A2515-500 500 mg
EUR 64
Description: Suitable for mammalian cell selection

Hygromycin B

A2813-100MG 100MG
EUR 39.6
Description: Cell Cuture

Hygromycin B

AG190 1 mg
EUR 627.6

Hygromycin B

HY-B0490 10mM/1mL
EUR 151.2

Hygromycin B

GA7834-1 1
EUR 95

Hygromycin B

GA7834-100 100
EUR 31.7

Hygromycin B

GA7834-100MG 100 mg
EUR 74.4

Hygromycin B

GA7834-1G 1 g
EUR 151.2

Hygromycin B

GA7834-5 5
EUR 379.6

Hygromycin B

GA7834-500 500
EUR 55.4

Hygromycin B

GA7834-500MG 500 mg
EUR 103.2

Hygromycin B

GA7834-5G 5 g
EUR 495.6

Hygromycin B

H007-1G 1 g
EUR 61.03
Description: C20H37N3O13

Hygromycin B

H007-500MG 500 mg
EUR 33.38
Description: C20H37N3O13

Hygromycin B

H007-5x1G 5 x 1 g
EUR 251.2
Description: C20H37N3O13

Hygromycin B

H997600 100mg
EUR 1759
Description: 31282-04-9

Hygromycin B

G265 1.0 g
EUR 350
Description: Hygromycin B is an aminoglycoside produced by Streptomyces hygroscopicus bacteria. This antibiotic kills fungi, bacteria, and even eukaryotic cells by blocking protein synthesis. Hygromycin B is often used in order to select for and sustain eukaryotic and prokaryotic cells that contain the hygromycin resistance gene.

Hygromycin B

T1022-10mg 10mg Ask for price
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Hygromycin B

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Hygromycin B

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Hygromycin B

T1022-50mg 50mg Ask for price
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Hygromycin B

T1022-5mg 5mg Ask for price
Description: Hygromycin B

Hygromycin B

abx082491-100l 100 µl
EUR 337.5

Hygromycin B

abx082491-1ml 1 ml Ask for price

Hygromycin B

abx082491-200l 200 µl Ask for price

Hygromycin B, 1g

R3128-1g each
EUR 362.4

Hygromycin B [BSA]

DAG4469 0.5mg
EUR 936

Hygromycin B [KLH]

DAG4485 0.5mg
EUR 1248

Hygromycin B, 10g

R3128 10g
EUR 1918.7

Hygromycin B, 10g

R3128-10g each
EUR 2724

Hygromycin B (HRP)

abx284211-100g 100 µg Ask for price

Hygromycin B (HRP)

abx284211-20g 20 µg
EUR 475

Hygromycin B (HRP)

abx284211-50g 50 µg Ask for price

Hygromycin B Solution

09287-84 20ML
EUR 107.8

HYGROMYCIN B SOLUTION

30-240-CR 20 mL/pk
EUR 188.4
Description: Media Catalog; Cell Culture Reagents

Hygromycin B Antibody

abx342220-100l 100 µl
EUR 4500

Hygromycin B Antibody

abx342220-50l 50 µl
EUR 900

EZSolution? Hygromycin B

2590-20 each
EUR 326.4

HYGROMYCIN B 1000 UNIT POWDER

H397 1G
EUR 259.3

Hygromycin B Concentrated

H001-1MU 1 MU
EUR 58.67
Description: C20H37N3O13

Hygromycin B EvoPure®

H010-1G 1 g
EUR 141.32
Description: C20H37N3O13

Hygromycin B EvoPure®

H010-500MG 500 mg
EUR 101.88
Description: C20H37N3O13

HYGROMYCIN B (100 mg/mL WATER)

H385 10ML
EUR 121.53

Hygromycin B::BSA Conjugate

40810006-1 5 mg
EUR 198.58

Hygromycin B::BSA Conjugate

40810006-2 20 mg
EUR 354.14

Hygromycin B::KLH Conjugate

40810007-1 5 mg
EUR 215.83

Hygromycin B::KLH Conjugate

40810007-2 20 mg
EUR 354.14

Hygromycin B Gold (solution)

ant-hg-1 1 g (10 x 1 ml)
EUR 144.9

Hygromycin B Gold (solution)

ant-hg-2 2 g (20 x 1 ml)
EUR 248.85

Hygromycin B Gold (solution)

ant-hg-5 5 g (1 x 50 ml)
EUR 460.95

HYGROMYCIN B (50 mg/mL PBS)

H370 20ML
EUR 121.53

50mg/mL Hygromycin B Solution

PB180126-10mL 10 mL
EUR 88
Description: Supplements & Reagents

50mg/mL Hygromycin B Solution

PB180126 10mL
EUR 88
Description: Antibiotics

Hygromycin B Deuterated (d4 major)

H997604 10mg
EUR 1471

Hygromycin B EvoPure (Low Endotoxin)

H024-1G 1g
EUR 456.05
Description: C20H37N3O13

Hygromycin B EvoPure (Low Endotoxin)

H024-500MG 500 mg
EUR 281.78
Description: C20H37N3O13

Hygromycin B Solution (Low Endotoxin)

H026-20ML 20 mL
EUR 77.55
Description: C20H37N3O13

Hygromycin Antibody

abx023698-1mg 1 mg
EUR 1312.8

Hygromycin Antibody

abx023699-1mg 1 mg
EUR 1312.8

Hygromycin Solution

Hygro-anti 1.0 ml (50 mg/ml)
EUR 70
Description: Hygromycin antibiotic selection solution in PBS

Hygromycin B Solution, 50mg/mL, Sterile

40810004-1 25 mL
EUR 80.99

Hygromycin B Solution, 50mg/mL, Sterile

40810004-2 50 mL
EUR 150.08

Hygromycin B Solution, 100mg/mL, Sterile

40810005-1 10 mL
EUR 94.19

Hygromycin B Solution (50 mg/ml in PBS Buffer)

H011-20ML 20 mL
EUR 70.47
Description: C20H37N3O13

Hygromycin B Solution (50 mg/ml in PBS Buffer)

H011-5x20ML 5x20mL
EUR 291.99
Description: C20H37N3O13

Escherichia coli Hygromycin-B 4-O-kinase (hph)

1-CSB-YP365448ENL
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Description: Recombinant Escherichia coli Hygromycin-B 4-O-kinase(hph) expressed in Yeast

Escherichia coli Hygromycin-B 4-O-kinase (hph)

1-CSB-EP365448ENL
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Description: Recombinant Escherichia coli Hygromycin-B 4-O-kinase(hph) expressed in E.coli

Escherichia coli Hygromycin-B 4-O-kinase (hph)

1-CSB-EP365448ENLa0
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Description: Recombinant Escherichia coli Hygromycin-B 4-O-kinase(hph) expressed in E.coli

Enhanced GFP Lentivirus (Hygromycin)

78639-H 500 µl x 2
EUR 835
Description: Enhanced green fluorescent protein (eGFP) is a modified (F64L and S65T mutations) version of the native GFP protein isolated from jellyfish (Aequorea victoria), with increased fluorescence and more efficient folding. The Enhanced GFP Lentivirus are replication-incompetent, HIV based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. These viruses constitutively express eGFP under a CMV promoter. eGFP expression and transduction efficiency can easily be verified and optimized via fluorescence microscopy or flow cytometry. eGFP has an excitation wavelength of 488 nm, an emission wavelength of 509 nm, and extinction coefficient of 55,000 M-1cm-1.

Hygromycin B EvoPure Solution (100 mg/ml in PBS Buffer)

H015-10x2ML 10 x 2 mL
EUR 225.86
Description: C20H37N3O13

Hygromycin B EvoPure Solution (100 mg/ml in PBS Buffer)

H015-5x2ML 5 x 2 mL
EUR 141.32
Description: C20H37N3O13

Hygromycin phosphotransferase antibody

10-1418 1 mg
EUR 600
Description: Mouse monoclonal Hygromycin phosphotransferase antibody

Hygromycin phosphotransferase antibody

10-1419 1 mg
EUR 600
Description: Mouse monoclonal Hygromycin phosphotransferase antibody

Hygromycin phosphotransferase antibody

10-1420 1 mg
EUR 600
Description: Mouse monoclonal Hygromycin phosphotransferase antibody

Hygromycin phosphotransferase antibody

10-1421 1 mg
EUR 600
Description: Mouse monoclonal Hygromycin phosphotransferase antibody

Cas9 Lentivirus (Hygromycin Selection)

78067 500 µl x 2
EUR 795
Description: Cas9 Lentivirus can be used to generate Cas9 expressing cells in almost any mammalian cell line. Cells stably expressing Cas9 can then be transduced or electroporated with sgRNA targeting a gene of interest to quickly generate knock-out cell pools or cell lines.

The Cas9 Lentiviruses are replication incompetent, HIV-based VSV-G pseudo-typed lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a Cas9 gene driven by an EF1a promoter, along with a Hygromycin selection marker._x000D_

Firefly Luciferase Lentivirus Hygromycin

79692-H 500 µl x 2
EUR 875
Description: The Firefly Luciferase Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells, including primary and non-dividing cells. These viruses constitutively express firefly luciferase under a CMV promoter.

MEF Feeder Cells (Hygromycin-resistant)

CBA-313 1 vial
EUR 553.2
Description: MEF Feeder Cells are mouse embryonic fibroblasts that allow stem cell culture without LIF. Cells must be mitotically inactivated prior to addition of stem cells. Hygromycin resistant.

Hygromycin Phosphotransferase (HPT) Antibody

abx018357-1mg 1 mg
EUR 512.5

Hygromycin Phosphotransferase (HPT) Antibody

abx018358-1mg 1 mg
EUR 512.5

Hygromycin Phosphotransferase (HPT) Antibody

abx018359-1mg 1 mg
EUR 512.5

Hygromycin Phosphotransferase (HPT) Antibody

abx018360-2ml 2 ml
EUR 512.5

Recombinant Escherichia coli Hygromycin-B 4-O-kinase (hph)

CSB-YP365448ENL 6406 mg Ask for price

Recombinant Escherichia coli Hygromycin-B 4-O-kinase(hph)

AP71180 1mg
EUR 2826

Recombinant Escherichia coli Hygromycin-B 4-O-kinase(hph)

AP72994 each Ask for price

Recombinant Escherichia coli Hygromycin-B 4-O-kinase(hph)

AP77479 each Ask for price

Recombinant Escherichia coli Hygromycin-B 4-O-kinase (hph)

CSB-EP365448ENL 3454 mg Ask for price

Recombinant Escherichia coli Hygromycin-B 4-O-kinase (hph)

CSB-EP365448ENLa0 3455 mg Ask for price

Recombinant Escherichia coli Hygromycin-B 4-O-kinase (hph)

RPC20138-100ug 100ug
EUR 721.6

Recombinant Escherichia coli Hygromycin-B 4-O-kinase (hph)

RPC20138-1mg 1mg
EUR 2884.7

Recombinant Escherichia coli Hygromycin-B 4-O-kinase (hph)

RPC20138-20ug 20ug
EUR 448.1

EF1a-(Red-Luciferase) Lentivirus (Hygromycin)

LVP1305 1x10^7 IFU/ml x 200ul
EUR 245
Description: Red-Luciferease expression lentivirus under EF1a promoter, containing Hygromycin selection.

Expression Negative Control Lentivirus (Hygromycin)

79902-H 500 µl x 2
EUR 795
Description: The Expression Negative Control Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The controls package the same virus particles as the target expression virus, but they do not express a specific protein under the CMV promoter. _x000D_The Expression Negative Control Lentivirus (G418) expresses the gene for aminoglycoside 3' phosphotransferase, which confers resistance to kanamycin, neomycin, and geneticin (G418)._x000D_The Expression Negative Control Lentivirus (Hygromycin) expresses the gene for hygromycin B phosphotransferase, which confers resistance to Hygromycin._x000D_The Expression Negative Control Lentivirus (Puromycin) expresses the gene for puromycin N-acetyl-transferase, which confers resistance to puromycin._x000D_ _x000D_

TCR Activator Lentivirus (EF1a Promoter/Hygromycin)

79894-EH 500 µl x 2
EUR 795
Description: The TCR Activator Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a gene for a membrane-bound, engineered T cell receptor (TCR) activator driven by a CMV promoter or an EF1a promoter. After transduction, the expression of TCR activator can be monitored in the target cells.

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His, Yeast-1mg

QP7397-ye-1mg 1mg
EUR 3296.4

Murashige and Skoog (MS) Medium Plates, w/ Hygromycin

30630060-1 20 Plate(s)
EUR 84.23

Murashige and Skoog (MS) Medium Plates, w/ Hygromycin

30630060-2 50 Plate(s)
EUR 173.72

Murashige and Skoog (MS) Medium Plates, w/ Hygromycin

30630060-3 25 Plate(s)
EUR 84.23

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His, Yeast-10ug

QP7397-ye-10ug 10ug
EUR 434.4

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His, Yeast-50ug

QP7397-ye-50ug 50ug
EUR 576

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His, Yeast-100ug

QP7397-ye-100ug 100ug
EUR 945.6

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His, Yeast-200ug

QP7397-ye-200ug 200ug
EUR 1512

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His, Yeast-500ug

QP7397-ye-500ug 500ug
EUR 2164.8

LEXSY Hygro, Hygromycin B, 1 ml (100 mg/ml) ** shipped on blue ice - must be shipped via overnight service

M-AB-104S 1 ml
EUR 86
Description: LEXSY Hygro, Hygromycin B, 1 ml (100 mg/ml) ** shipped on blue ice - must be shipped via overnight service

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His-SUMO, E.coli-1mg

QP7397-ec-1mg 1mg
EUR 2763.6

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His-SUMO, E.coli-100ug

QP7397-ec-100ug 100ug
EUR 848.4

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His-SUMO, E.coli-10ug

QP7397-ec-10ug 10ug
EUR 391.2

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His-SUMO, E.coli-200ug

QP7397-ec-200ug 200ug
EUR 1338

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His-SUMO, E.coli-500ug

QP7397-ec-500ug 500ug
EUR 1816.8

Recombinant E.coli Hygromycin-B 4-O-kinase Protein, His-SUMO, E.coli-50ug

QP7397-ec-50ug 50ug
EUR 522

LEXSY Hygro, Hygromycin B, 5 x 1 ml (100 mg/ml) ** shipped on blue ice - must be shipped via overnight service

M-AB-104L 5 x 1 ml
EUR 294
Description: LEXSY Hygro, Hygromycin B, 5 x 1 ml (100 mg/ml) ** shipped on blue ice - must be shipped via overnight service

EF1a-(Red-Luciferase) Lentivirus (Hygromycin), Concentrated Lentivirus

LVP1305-PBS 1x10^8 IFU/ml x 200ul
EUR 455
Description: concentrated lentivirus in PBS express Red-Luciferease under EF1a promoter, containing Hygromycin selection.

ELISA PLATE READER : MICRO READ 1000

1000 1 unit
EUR 2628

ELISA PLATE WASHER : MICRO WASH 1100

1100 1 unit
EUR 2403.6

ELISA PLATE SHAKER : MICRO SHAKE 1200

1200 1 unit
EUR 916.8

Testo 608-1 Hygrometer - EACH

HYG4000 EACH
EUR 126.32

Testo 608-2 Hygrometer - EACH

HYG4002 EACH
EUR 180.66

Hanna Hygrometer Case - EACH

HYG2083 EACH
EUR 91.8

Hanna Thermo Hygrometer HI 9564 - EACH

HYG2020 EACH
EUR 299.7

Thermometer/hygrometer - EACH

DD98463 EACH
EUR 29.7

Digital Thermometer Hygrometer

THE1168 EACH
EUR 38.4

Aluminum Glove Box 34" x 20" w/ spill tray & hygrometer

108CGB24-20 each
EUR 1797

Aluminum Glove Box 27" x 20" w/ spill tray & hygrometer

108CGB27-20 each
EUR 2146

Aluminum Glove Box 34" x 20" w/ spill tray & hygrometer

108CGB34-20 each
EUR 2211

Digital Thermometer Hygrometer - EACH

THE1162 EACH
EUR 31.87

pBC- Hygro

PVT5305 2 ug
EUR 390

pLKO.1- Hygro

PVT11107 2 ug
EUR 361.2

LEXSY Hygro

AB-104L 5 x 1ml
EUR 236.2

LEXSY Hygro

AB-104S 1ml
EUR 69.1

SEAP (EF1a, Hygro)

LVP1200 1x107 IFU/ml x 200ul
EUR 418.8
Description: Lentivirus express SEAP under EF1a promoter, containing Hygromycin selection.

pWZL hygro 12S E1A

PVT14501 2 ug
EUR 843.6

pCDNA3.1- Hygro

PVT10675 2 ug
EUR 361.2

Hygrolidin

574173 1.0mg
EUR 510

Hygrolidin

ADC-P-099 unit Ask for price

Hygrolidin

H033-1MG 1 mg
EUR 207.65
Description: C38H58O11

Hygrolidin

H033-5MG 5 mg
EUR 726.13
Description: C38H58O11

SEAP (EF1a, Hygro) in PBS

LVP1200-PBS 1x107 IFU/ml x 200ul
EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter, containing Hygromycin selection.

pCDH- CMV- MCS- EF1- Hygro

PVT11076 2 ug
EUR 444

pGL4.15[luc2P Hygro]

PVT17664 2 ug
EUR 360

Hygrolidin

T38243-10mg 10mg Ask for price
Description: Hygrolidin

Hygrolidin

T38243-1g 1g Ask for price
Description: Hygrolidin

Hygrolidin

T38243-1mg 1mg Ask for price
Description: Hygrolidin

Hygrolidin

T38243-50mg 50mg Ask for price
Description: Hygrolidin

Hygrolidin

T38243-5mg 5mg Ask for price
Description: Hygrolidin

SEAP (TetCMV, Hygro)

LVP1191 1x107 IFU/ml x 200ul
EUR 418.8
Description: Lentivirus express SEAP under optional inducible TetCMV promoter, containing Hygromycin selection.

pGL4.43[Luc29 XPE Hygro]

PVT14287 2 ug
EUR 843.6

We identify PIK3CA, RHOA, MAPK3, PAFAY1B1, CTNNB1, MYC, PRKCA, ERBB2, and CDC42 as a key gene on the MIR-375 network which is set and estimates the possible function of the MIR-375 in the heart muscle, which consists mainly in regulations on signaling paths that are dependent on on RHO-GTPases. We apply our algorithm to predict Mirna’s function into the python module, which is available at GitHub.

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