Adenovirus Onkolytic is being developed as a new anti-cancer agent. The efficacy can be increased by entering the RNA Interference (RNAI) molecule. RNai molecules can be expressed in various precursor formats. The purpose of this study is to determine the most effective format.

For this purpose, we built three types of adenovirus onkolytic type δ24, with cassette microrna-1 expressions (MIR-1) in short hair RNA (Shrum), precursor microrna (pre-mirna), and primary mirna format (pri-mirna) (pri-mirna) ( pri-mirna), respectively. Viruses compared to viral replication, mature-1 expression mature, and target genes silence cancer cells. Combining cassettes only have small effects on viral replication. Ripe mature expression of the pri-mirna format reaches an average 100 times higher than two other formats.

This expression remains stable after a long-term viral propagation. Infection with a virus that expressed the PRI-MIR-1 silenced the MIR-1 target that was validated by FOXP1 and met. Drosha Knockout almost completely cancels mature-1 expression mature, confirming that the processing of adenovirus-coded pri-mir-1 depends on the Mirna Machine inang. Using Simple Vitro Recombination Cloning, the same virus expressed MIR-26B made and shown to silence the MIR-26B validated PTGS2 target. Thus we provide platforms for adenovirus onkolytic construction with high expression of selected RNAI molecules.

Biological Implications and Clinical Potential Metastasis related to Mirna in Colorectal Cancer

Colorectal cancer (CRC), ranking as the third most common cancer, leads to a very high mortality rate. Metastasis is the main cause of poor results in CRC. When metastases occur, the survival rate of 5 years the patient decreases sharply, and a strategy to increase the patient’s life seems limited. Microrna (MIRNAS) evolutionariously preserved small non-coding RNA which was significantly involved in crc ferocious phenyel manipulation, including proliferation, invasion, and metastasis. Until now, the accumulation of studies has disclosed certain Mirnas mechanisms and functions in CRC metastasis.

However, there is no systematic discussion of biological implications and clinical potential (diagnostic role, the role of the prognostic, and the potential for targeted therapy) of MIRNA-related metastases in CRC. This review mainly summarizes the recent progress of minna metastasis which is mediated in CRC. We also discuss the clinical values ​​of MIRNAS regarding metastasis as candidates for biomarkers or therapeutic targets in CRC. In addition, we imagine future orientation and challenges in translating these findings into clinical applications.

Non-coding RNA as Biomarker Prognostic: Mirna’s signature specifically for aggressive initial lungsinoma lungsinoma

Lung cancer burden can be reduced by adopting primary and secondary prevention strategies such as anti-smoking campaigns and low-dose CT screening for high-risk subjects (aged> 50 and smokers> 30 packs / year). The CT screening test recently showed a stage shift towards the previous stage of lung cancer and reduction of mortality (~ 20%). However, the patient faction is quite large (30-50%) with the initial disease still experiencing recurrence and adverse prognosis.

Thus, the identification of effective prognostic biomarkers in the current stage of lung cancer is the most important. Here, we apply a multi-tier approach that relies on RNA-SEQ and analysis of the Mirna-SEQ data of a large cohort of lung cancer patients (TCGA-LUB, N = 510), which allows us to identify the signature of the prognostic Mirna in the stage I adenocarcinoma lungs. Such signatures show high accuracy (AUC ranges from 0.79 and 0.85) in printing aggressive diseases.

What is important, using a network-based approach, we replay the Mirna-MRNA regulation network, identify a minimum signature of 7 MIRNAS, which is validated in the FFPE lung adenocarcinoma group (CSS, N = 44) and controls various overlapping genes with pathways relevant cancer. Our results further indicate the reliability of Mirna-based biomarkers for the prognostication of lung cancer and make steps forward to the Mirna Biomarkers application in clinical routines.

Mirna’s profile of cellular, extracellular and extracellular from pre-ovulation follicles show signaling disorders in polycystic ovaries

The cell-free RNA has the potential to act as a means of gene expression regulations between cells and therefore it is used as a diagnostic marker that describes the network environment. Origin and RNA functions in human ovarian follicles, oocyte maturation environment, are not clear. The current study investigates the difference in fertile women’s Michorna profiles and polycystic ovarian syndrome (PCOS) in three compartments of the same preovulation follicles: mural granulose cells (MGC), cell free cell fluid (FF), and extracellular vesicles (EV) of FF with Small RNA sequencing. In Silico analysis it is used for predictions and representation of over-representation of pathways targeted for Detected Microrna.

PCOS follicles are distinguished from normal networks with a differential expression of 30 microrna in MGC and 10 microrna in FF (FDR <0.1) which usually regulates the cytokine signaling path. The concentration of EV-S is higher at FF Patos Patients (P = 0.04) containing eight microrna expressed differently (p <0.05).

PBS Tablets (1000 ml)
2129-10	Biovision	each	EUR 196.8

PBS Tablets (1000 ml)
2129-100	Biovision	each	EUR 764.4

PBS Tablets (100 ml)
2865-100	Biovision	each	EUR 196.8

PBS Wash Buffer Pack
AR1155	BosterBio	500mL/pack	EUR 78

10x PBS Buffer Solution
BA01802	Bioatlas	6x100ml	EUR 116.4
Description: High purity buffer for various PCR applications.

ToxOut? Endotoxin Free PBS
7943-50	Biovision	each	EUR 222

EZBlock? (PBS) Blocking Buffer
2128-1000	Biovision	each	EUR 274.8

EZBlock? (PBS) Blocking Buffer
2128-200	Biovision	each	EUR 164.4

10 x PBS, pH 7.30
GR103004x10	Genorise Scientific	1 L	EUR 84

20 x PBS, pH 7.30
GR103004x20	Genorise Scientific	1 L	EUR 135

Phosphate Buffered Saline (PBS)
2113-500	Biovision	each	EUR 164.4

Phosphate Buffered Saline(PBS)
MED1390	Scientific Laboratory Supplies	EACH	EUR 33.6

SEAP (CAG, Bsd) in PBS
LVP1203-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under CAG promoter, containing Blasticidin selection.

SEAP (CAG, Neo) in PBS
LVP1204-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP unde CAG promoter, containing Neomycin selection.

1X PBS Buffer , pH 7.4
P2101-050	GenDepot	500ml	EUR 79.2

1X PBS Buffer , pH 7.4
P2101-100	GenDepot	1L	EUR 105.6

SEAP (EF1a, Bsd) in PBS
LVP1194-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter, containing Blasticidin selection.

SEAP (EF1a, Neo) in PBS
LVP1195-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP unde EF1a promoter, containing Neomycin selection.

SEAP (EF1a, Zeo) in PBS
LVP1201-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter, containing Zeomycin selection.

SEAP (CAG, Puro) in PBS
LVP1202-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under CAG promoter, containing puromycin selection.

SEAP (EF1a, GFP) in PBS
LVP1217-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter with GFP fluorescent marker.

SEAP (EF1a, RFP) in PBS
LVP1218-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter with RFP fluorescent marker.

SEAP (Ubc, Puro) in PBS
LVP1219-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under Ubc promoter, containing puromycin selection.

10X PBS Buffer , pH 7.4
P2100-050	GenDepot	500ml	EUR 105.6

10X PBS Buffer , pH 7.4
P2100-100	GenDepot	1L	EUR 109.2

SEAP (EF1a, Puro) in PBS
LVP1193-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter, containing puromycin selection.

SEAP (mPGK, Puro) in PBS
LVP1220-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under mPGK promoter, containing puromycin selection.

SEAP (ActB, Puro) in PBS
LVP1221-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under ActB promoter, containing puromycin selection.

PBS 1X, pH 7.4 solution
GB4757-1	Glentham Life Sciences	1	EUR 27.1

PBS 1X, pH 7.4 solution
GB4757-500	Glentham Life Sciences	500	EUR 18.1

SEAP (TetCMV, Bsd) in PBS
LVP1185-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter, containing Blasticidin selection.

SEAP (TetCMV, Neo) in PBS
LVP1186-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter, containing Neomycin selection.

SEAP (TetCMV, Zeo) in PBS
LVP1192-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter, containing Zeomycin selection.

SEAP (EF1a, Hygro) in PBS
LVP1200-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter, containing Hygromycin selection.

SEAP (TetCMV, GFP) in PBS
LVP1215-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter with GFP fluorescent marker.

SEAP (TetCMV, RFP) in PBS
LVP1216-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter with RFP fluorescent marker.

PBS 10X, pH 7.4 solution
GB4924-1	Glentham Life Sciences	1	EUR 48.2

PBS 10X, pH 7.4 solution
GB4924-500	Glentham Life Sciences	500	EUR 27.1

SEAP (TetCMV, Puro) in PBS
LVP1184-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter, containing puromycin selection.

SEAP (TetCMV, Hygro) in PBS
LVP1191-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter, containing Hygromycin selection.

10x PBS Ready Mixed Powder
BA01701	Bioatlas	1L	EUR 81.6
Description: High purity buffer for various PCR applications.

PBS Blocking buffer with BSA
SB0626	Bio Basic	1pk, 1L	EUR 100.72

AR-GFP (Bsd) Lentivirusin PBS
LVP912-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

10X PBS MaxTag Histo (OKRA00043)
OKRA00043	Aviva Systems Biology	100 ml	EUR 168
Description: Description of target: ;Species reactivity: ;Application: ;Assay info: ;Sensitivity:

PBS pH 7.0 +/- 0.2 at 22C
PBS255	Scientific Laboratory Supplies	5L	EUR 155.37

EZBlock? T20 (PBS) Blocking Buffer
2143-1000	Biovision	each	EUR 261.6

EZBlock? T20 (PBS) Blocking Buffer
2143-200	Biovision	each	EUR 144

ARE-GFP (Puro) Lentivirusin PBS
LVP981-P-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter that embedded 4 tandem repeats of antioxidant response element (ARE). This lentivirus also contain the puromycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

10 X PBST (PBS with Tween 20)
GR103013	Genorise Scientific	1 L	EUR 99

PBST (PBS-Tween 20), 10X pH 7.4
18-173	Genesee Scientific	500ml/Unit	EUR 311

PBST (PBS-Tween 20), 10X pH 7.4
18-174	Genesee Scientific	1000ml/Unit	EUR 352

1L PBS Phosphate-Buffered Saline
21-040-CM	Scientific Laboratory Supplies	PK6	EUR 105.6

Phosphate Buffered Saline (PBS) Powder
AR0030	BosterBio	2000mL/pack	EUR 63.6

Accuris QuickSilver PBS Buffer Powder
EB1200	Scientific Laboratory Supplies	PK100	EUR 199.2

PBS (Phosphate Buffered Saline) Powdered
PD0100	Bio Basic	1PK, 10L	EUR 74.62

SEAP (CAG, RFP-Bsd) in PBS
LVP1205-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under CAG promoter with RFP fluorescent marker, containing Blasticidin selection.

SEAP (CAG, GFP-Bsd) in PBS
LVP1207-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under CAG promoter with GFP fluorescent marker, containing Blasticidin selection.

SEAP (EF1a, RFP-Bsd) in PBS
LVP1196-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter with RFP fluorescent marker, containing Blasticidin selection.

SEAP (EF1a, GFP-Bsd) in PBS
LVP1198-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter with GFP fluorescent marker, containing Blasticidin selection.

SEAP (CAG, RFP-Puro) in PBS
LVP1206-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under CAG promoter with RFP fluorescent marker, containing Puromycin selection.

SEAP (CAG, GFP-Puro) in PBS
LVP1208-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under CAG promoter with GFP fluorescent marker, containing Puromycin selection.

SEAP (EF1a, RFP-Puro) in PBS
LVP1197-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter with RFP fluorescent marker, containing Puromycin selection.

SEAP (EF1a, GFP-Puro) in PBS
LVP1199-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under EF1a promoter with GFP fluorescent marker, containing Puromycin selection.

Dilution Buffer [1x PBS pH 7.3]
0209B	AthenaES	100 ml	EUR 92.4

PBS-Tween® Tablets (1000 ml)
2130-100	Biovision	each	EUR 836.4

PBS-Tween® Tablets (1000 ml)
2130-10	Biovision	each	EUR 210

Apex PBS Buffer 10X Dry Pack
20-134	Genesee Scientific	1 Pack/Unit	EUR 280

SEAP (TetCMV, RFP-Bsd) in PBS
LVP1187-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter with RFP fluorescent marker, containing Blasticidin selection.

SEAP (TetCMV, GFP-Bsd) in PBS
LVP1189-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Lentivirus express SEAP under optional inducible TetCMV promoter with GFP fluorescent marker, containing Blasticidin selection.

Phosphate Buffered Saline (PBS) pH 7.4, 1000 ml
09-9400-100	Medicago	1000 ml	EUR 316.8

Phosphate Buffered Saline (PBS) pH 7.4, 1000 ml
09-9400-30	Medicago	1000 ml	EUR 190.8

Phosphate Buffered Saline (PBS) pH 7.2, 1000 ml
09-9499-100	Medicago	1000 ml	EUR 316.8

Phosphate Buffered Saline (PBS) pH 7.2, 1000 ml
09-9499-30	Medicago	1000 ml	EUR 193.2

Papain Solution In PBS, 1mg/ml
CA093-002	GenDepot	20ml	Ask for price

CRE (Neo), CMV lentivirus, in PBS
LVP297-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase with Neomycin marker. Virus concentrated and buffer changed into provided in PBS solution

CRE (Bsd), CMV lentivirus in PBS
LVP336-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase with Blasticidin marker. Virus concentrated and buffer changed into provided in PBS solution

CRE (Bsd), CAG lentivirus in PBS
LVP574-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase under CAG promoter with Blasticidin marker. Virus concentrated and buffer changed into provided in PBS solution

CRE (Neo), CAG lentivirus, in PBS
LVP575-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase under CAG promoter with Neomycin marker. Virus concentrated and buffer changed into provided in PBS solution

SEAP (TetCMV, RFP-Puro) in PBS
LVP1188-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter with RFP fluorescent marker, containing Puromycin selection.

SEAP (TetCMV, GFP-Puro) in PBS
LVP1190-PBS	GenTarget	1x107 IFU/ml x 200ul	EUR 852
Description: Concentrated Lentivirus express SEAP under optional inducible TetCMV promoter with GFP fluorescent marker, containing Puromycin selection.

CRE (Puro), CMV lentivirus in PBS
LVP339-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase with puromycin marker. Virus concentrated and buffer changed into provided in PBS solution

CRE (Bsd), EF1a lentivirus in PBS
LVP519-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase under EF1a promoter with Blasticidin marker. Virus concentrated and buffer changed into provided in PBS solution

CRE (Neo), EF1a lentivirus, in PBS
LVP521-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase under EF1a promoter with Neomycin marker. Virus concentrated and buffer changed into provided in PBS solution

CRE (Puro), CAG lentivirus in PBS
LVP573-PBS	GenTarget	5 x107 IFU/ml x 200ul	EUR 852
Description: Pre-made lentiviral particles expressing nuclear permeable CRE recombinase under CAG promoter with puromycin marker. Virus concentrated and buffer changed into provided in PBS solution

AR-GFP (Neo) Lentivirus  in PBS
LVP912-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-GFP (RFP) Lentivirus in PBS
LVP912-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-RFP (Bsd) Lentivirus in PBS
LVP913-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-RFP (GFP) Lentivirus in PBS
LVP913-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the GFP selection marker under the consitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-RFP (Neo) Lentivirus in PBS
LVP913-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-Luc (Bsd) Lentivirus in PBS
LVP914-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE).. This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-Luc (GFP) Lentivirus in PBS
LVP914-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the GFP selection marker under the consitutiveRSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-Luc (Neo) Lentivirus  in PBS
LVP914-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

AR-Luc (RFP) Lentivirus in PBS
LVP914-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under the minimal promoter contains 4 tandem repeats of Androgen Response Element (ARE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-GFP (Bsd) Lentivirus in PBS
LVP949-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-GFP (Neo) Lentivirus in PBS
LVP949-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-GFP (RFP) Lentivirus in PBS
LVP949-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-RFP (Bsd) Lentivirus in PBS
LVP950-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-RFP (GFP) Lentivirus in PBS
LVP950-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the GFP selection marker under the consitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-RFP (Neo) Lentivirus in PBS
LVP950-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-Luc (Bsd) Lentivirus in PBS
LVP951-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-Luc (GFP) Lentivirus in PBS
LVP951-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the GFP selection marker under the consitutiveRSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-Luc (Neo) Lentivirus in PBS
LVP951-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

G_RE-Luc (RFP) Lentivirus in PBS
LVP951-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter embedded 4 tandem repeats of glucocorticoid response element (G-RE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-GFP (Bsd) Lentivirus in PBS
LVP969-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-GFP (Neo) Lentivirus in PBS
LVP969-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-GFP (RFP) Lentivirus in PBS
LVP969-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-RFP (Bsd) Lentivirus in PBS
LVP970-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-RFP (GFP) Lentivirus in PBS
LVP970-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the GFP selection marker under the consitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-RFP (Neo) Lentivirus in PBS
LVP970-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-Luc (Bsd) Lentivirus in PBS
LVP971-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-Luc (GFP) Lentivirus in PBS
LVP971-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the GFP selection marker under the consitutiveRSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-Luc (Neo) Lentivirus in PBS
LVP971-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

H_RE-Luc (RFP) Lentivirus in PBS
LVP971-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 6 tandem repeats of hypoxia transcriptional response element (H-RE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-GFP (Bsd) Lentivirus in PBS
LVP973-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-GFP (Neo) Lentivirus in PBS
LVP973-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-GFP (RFP) Lentivirus in PBS
LVP973-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-RFP (Bsd) Lentivirus in PBS
LVP974-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-RFP (GFP) Lentivirus in PBS
LVP974-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the GFP selection marker under the consitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-RFP (Neo) Lentivirus in PBS
LVP974-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express RFP reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-Luc (Bsd) Lentivirus in PBS
LVP975-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-Luc (GFP) Lentivirus in PBS
LVP975-G-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the GFP selection marker under the consitutiveRSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-Luc (Neo) Lentivirus in PBS
LVP975-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

ER-Luc (RFP) Lentivirus in PBS
LVP975-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express Firefly luciferase reporter under a minimal promoter that embedded 4 tandem repeats of estrogen receptor response element (ER-RE). This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

MB-GFP (Bsd) Lentivirus in PBS
LVP1021-B-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under human Myoglobin 's promoter which only expressed in muscle, predominantly in cardiac and skeletal myocytes. This lentivirus also contain the Blasticidin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

MB-GFP (Neo) Lentivirus in PBS
LVP1021-N-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under human Myoglobin 's promoter which only expressed in muscle, predominantly in cardiac and skeletal myocytes. This lentivirus also contain the Neomycin selection marker under RSV promoter. Lentivirus concentrated and provided in PBS solution.

MB-GFP (RFP) Lentivirus in PBS
LVP1021-R-PBS	GenTarget	1x108 IFU/ml x 200ul	EUR 852
Description: Pre-made lentivirus express GFP reporter under human Myoglobin 's promoter which only expressed in muscle, predominantly in cardiac and skeletal myocytes. This lentivirus also contain the RFP selection marker under the constitutive RSV promoter. Lentivirus concentrated and provided in PBS solution.

In addition, we present the Microrna MGC, FF, and EV profiles in fertile follicles and show that micrornas are loaded into EVS targeting Mr.NNAS from different signaling paths compared to Microrna on FF. To conclude, three follicular compartments play different roles in signaling disorders associated with PCOS.