Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs

Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs

Background: Metastatic disease caused by prostate cancer (PCa) is the leading cause of PCa-related death. RNA long non-protein-coding may have a significant cellular functions. Plasmasitoma variant translocation 1 (PVT1), long non-coding RNA genes encoded by human PVT1, is an oncogene, which can set up multiple tumor-associated genes. In PCa, function and PVT1 mechanism is not clear. NOP2 being pursued as a prognostic marker for cancer aggressiveness, which promotes the growth of mouse fibroblast and tumor formation. Basically, nothing is known about the specific interaction between PVT1 and NOP2.


Methods: 190 pairs of PCa tissue and adjacent normal tissue were collected and RNA sequencing was used to identify differential lncRNAs. Real-time quantitative real-time PCR (RT-qPCR) confirmed these results and the relationship of gene regulation. PVT1 lentiviral vectors are used to alter and genes to analyze their effects on the development of PCa. Transwell migration and invasion assays were performed to test the ability of metastasis. Biofunction of PVT1 and NOP2 confirmed in vitro and in vivo.


Results
: In this study, we report that long noncoding RNA-PVT1 is upregulated in PCa tissue promoted metastasis and PCa cell migration in vitro and their metastasis in vivo. High levels were significantly downregulated PVT1 tumor suppressor microRNAs (miRNAs), such as miR-15b-5p, miR-27a-3p, miR-143-3p, and miR-627-5p, levels in metastatic tissues are low compared with those in non-metastatic tissues. In vitro and in vivo, PVT1 promote PCa metastasis by targeting miRNAs. In addition, expression levels associated with the expression of positive PVT1 NOP2, cancer metastasis-associated protein. We show that promoted the invasion and migration NOP2 PCa. For certain mechanisms, correlation analysis showed that PVT1 promoted metastasis to up-regulate NOP2.


Conclusion: Overall, our results indicate that PVT1 acts as an inducer of PCa metastasis by targeting miRNAs, thus increasing NOP2. This axis may have diagnostic and therapeutic potential for advanced PCa.

 Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs
Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs

Screening of potential microRNAs associated with pancreatic cancer: Data mining based on RNA sequencing and microarray

Pancreatic cancer is a malignant tumor of the digestive tract, rendering it difficult to make an accurate diagnosis. 5-year survival rate for pancreatic cancer is <1%, and surgical resection is rarely proven to be effective. Therefore, the identification of more effective methods for early detection of pancreatic cancer is an urgent need. This study aims to explore key genes and microRNAs (miRNAs) associated with the pathogenesis of pancreatic cancer. public databases were searched, and the integrated data from The Cancer Genome Atlas and Gene Expression Omnibus database, which leads to the identification of 23 miRNAs that are expressed differently (DE-miRNA).

Four of DE-regulated miRNAs (miR-892b-HSA, HSA-miR-194-2, miR-200a-HSA and HSA-miR-194-1), while the DE-19 downregulated miRNA (hsa- Mirza 424, HSA-mir-191, mir-484-HSA, HSA-miR-142, miR-15b-HSA, HSA-miR-450A-1, HSA-mir-423, mir-126-HSA, hsa- Mirza 505, HSA-miR-16-1, HSA-miR-342, miR-130A-HSA, HSA-miR-3613, HSA-miR-450A-2, HSA-miR-26b, miR-451-HSA, HSA- miR-19b-2, HSA-miR-106A and HSA-miR-503) were identified using a cut-off criteria of P <0.05 and | log 2FC |> 1.0.

MCF7 Cell Slide (Human (69 yrs, Female) mammary gland, breast, epithelial adenocarcinoma) (5 slides/pk)

HCLS-17012 1 pk
EUR 300

BKS DB Mouse Mammary Microvascular Endothelial Cells

ABC-TC5487 1 vial Ask for price
Description: BKS db Mouse Mammary Microvascular Endothelial Cells are isolated from the mammary microvascular of Mice homozygous for the diabetes spontaneous mutation (Lepr/db) manifest morbid obesity, chronic hyperglycemia, pancreatic beta cell atrophy and become hypoRIemic. BKS db Mouse Mammary Microvascular Endothelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 2 min and incubated in Gentaur's Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells at passage 3 are detached from flasks and immediately cryopreserved in vials. Each vial contains at least 0.5×106 cells per ml. The method we use to isolate primary endothelial cells was developed based on a combination of established and our proprietary methods. These cells are pre-coated with PECAM-1 antibody, following the application of magnetic beads pre-coated with secondary antibody.

BALB/c Mouse Mammary Microvascular Endothelial Cells

ABC-TC3092 1 vial Ask for price
Description: BALB/c Mouse Mammary Microvascular Endothelial Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Mammary Microvascular Endothelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and are delivered frozen.Mouse Mammary Microvascular Endothelial Cells can be used in assays of cell to cell adhesion, migration, vascular tube formation, or transendothelial resistance (TER). Standard biochemical procedures performed with endothelial cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

C57BL/6 Mouse Mammary Microvascular Endothelial Cells

ABC-TC3219 1 vial Ask for price
Description: C57BL/6 Mouse Mammary Microvascular Endothelial Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Mammary Microvascular Endothelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and are delivered frozen.Mouse Mammary Microvascular Endothelial Cells can be used in assays of cell to cell adhesion, migration, vascular tube formation, or transendothelial resistance (TER). Standard biochemical procedures performed with endothelial cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Rat Mammary Microvascular Endothelial Cells

ABC-TC4168 1 vial Ask for price
Description: Rat Mammary Microvascular Endothelial Cells from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Mammary Microvascular Endothelial Cells are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and are delivered frozen.Rat Mammary Microvascular Endothelial Cells can be used in assays of cell to cell adhesion, migration, vascular tube formation, or transendothelial resistance (TER). Standard biochemical procedures performed with endothelial cell cultures include PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Human Mammary Microvascular Endothelial Cells

ABC-TC3696 1 vial Ask for price
Description: Vascular endothelial cells line the blood vessels and contribute to many biological processes such as hematosis, coagulation, trafficking of lymphocytes, and the inflammatory response. The endothelial cell is of primary importance in the extravasation of leukocytes from the circulation into sites of tissue inflammation. In the case of mastitis, the magnitude and duration of inflammation can be related to such parameters as endothelial adhesion molecules expression, cytokine secretion, as well as changes in vascular permeability. Histological study demonstrates that mammary microvasculature is a prominent feature of intralobular tissue and the endothelial cells play an important role in the study of mastitis and associated mammary gland immunopathology. HMMEC from Gentaur Research Laboratories are isolated from human breast tissue. HMMEC are cryopreserved after purification and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HMMEC are characterized by immunofluorescent method with antibodies to vWF/Factor VIII and CD31 (P-CAM) and by uptake of DiI-Ac-LDL. HMMEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HMMEC are guaranteed to further expand for 15 population doublings at the conditions provided by Gentaur Research Laboratories.

Human Primary Mammary Microvascular Endothelial Cells

T5440 5x10^5 cells / 1.0 ml
EUR 865

BALB/c Mouse Mammary Fibroblasts

ABC-TC3091 1 vial Ask for price
Description: BALB/c Mouse Primary Mammary Fibroblasts from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Primary Mammary Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Primary Mammary Fibroblasts are negative for bacteria, yeast, fungi, and mycoplasma. Cells are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining. Cells can be expanded for 3-5 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include the assay of cell to cell interaction, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

C57BL/6 Mouse Mammary Fibroblasts

ABC-TC3218 1 vial Ask for price
Description: C57BL/6 Mouse Primary Mammary Fibroblasts from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Primary Mammary Fibroblasts are grown in T25 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Primary Mammary Fibroblasts are negative for bacteria, yeast, fungi, and mycoplasma. Cells are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining. Cells can be expanded for 3-5 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with cell cultures include the assay of cell to cell interaction, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining, flow cytometry or generating cell derivatives for desired research applications.

Mouse Mammary carcinoma Marker ELISA

E01A23334 96T
EUR 700
Description: ELISA

BALB/c Mouse Mammary Epithelial Cells

ABC-TC3090 1 vial Ask for price
Description: BALB/c Mouse Primary Mammary Epithelial Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Primary Mammary Epithelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based coating solution for 0.5 hour and incubated in Gentaur's Culture Complete Growth Medium for 3-7 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Primary Mammary Epithelial Cells can be used in assays of cell to cell adhesion and migration. Standard biochemical procedures performed with epithelial cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

C57BL/6 Mouse Mammary Epithelial Cells

ABC-TC3217 1 vial Ask for price
Description: C57BL/6 Mouse Primary Mammary Epithelial Cells from Gentaur are isolated from tissue of pathogen-free laboratory mice. Mouse Primary Mammary Epithelial Cells are grown in T25 tissue culture flasks pre-coated with gelatin-based coating solution for 0.5 hour and incubated in Gentaur's Culture Complete Growth Medium for 3-7 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Mouse Primary Mammary Epithelial Cells can be used in assays of cell to cell adhesion and migration. Standard biochemical procedures performed with epithelial cell cultures include RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Mouse Mammary carcinoma Marker ELISA kit

E03M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mammary carcinoma Marker ELISA kit

E03M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mammary carcinoma Marker ELISA kit

E03M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Primary Mammary Smooth Muscle Cells

T4551 5x10^5 cells / 1.0 ml Ask for price

Immortalized Mouse Mammary Epithelial Cells (iMMEC)

T0451 1x106 cells / 1.0 ml Ask for price

Mammary Dissociation System 3 (Epithelial), Mouse

4-20323 ea Ask for price

Mouse mammary caFAinoma Marker-CA153 ELISA Kit

CN-02754M1 96T
EUR 549.6

Mouse mammary caFAinoma Marker-CA153 ELISA Kit

CN-02754M2 48T
EUR 368.4

Mouse mammary carcinoma Marker-CA153 ELISA Kit

CSB-E08272m-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse mammary carcinoma Marker-CA153 in samples from serum, plasma, homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse mammary carcinoma Marker-CA153 ELISA Kit

1-CSB-E08272m
  • EUR 1135.20
  • EUR 6938.40
  • EUR 3672.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse mammary carcinoma Marker-CA153 in samples from serum, plasma, homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Mammary carcinoma Aarker-CA153 ELISA Kit

EMM0228 96Tests
EUR 625.2

Mouse mammary carcinoma Marker-CA153 ELISA Kit

GA-E0541MS-48T 48T
EUR 403.2

Mouse mammary carcinoma Marker-CA153 ELISA Kit

GA-E0541MS-96T 96T
EUR 640.8

Mouse mammary carcinoma Marker-CA153 ELISA Kit

SL0371Mo -
EUR 528

Mouse mammary carcinoma Marker-CA153)ELISA Kit

QY-E20963 96T
EUR 433.2

Mouse mammary carcinoma Marker-CA153 Elisa Kit

EK731394 96 Wells
EUR 0.78

Mouse mammary carcinoma Marker-CA153 ELISA Kit

YLA0895MO-48T 48T
EUR 465

Mouse mammary carcinoma Marker-CA153 ELISA Kit

YLA0895MO-96T 96T
EUR 600

Mouse mammary carcinoma Marker-CA153 GENLISA ELISA

KLM0528 1 x 96 wells
EUR 341

Rat Mammary Fibroblasts

ABC-TC4167 1 vial Ask for price
Description: Rat Primary Mammary Fibroblasts from Gentaur are isolated from tissue of adult Sprague-Dawley Rats. Rat Primary Mammary Fibroblasts are grown in T75 tissue culture flasks pre-coated with gelatin-based solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1x10^6 cells per ml and is delivered frozen.Cells are negative for bacteria, yeast, fungi, and mycoplasma. Rat Primary Mammary Fibroblasts are tested for expression of marker using the antibody of anti-FSP1/S100A4 by immunofluorescence staining and can be expanded by 2-4 passages at a split ratio of 1:2 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with fibroblast cultures include the assays of cell to cell interaction, PCR, Western blotting, immunoprecipitation, immunofluorescent staining, immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Mouse FibrOut 1, for adipose, fat, eye, lung, mammary

4-21501 1 ml Ask for price

Mouse FibrOut 1, for adipose, fat, eye, lung, mammary

4-21502 5 x 1 ml Ask for price

Mouse mammary carcinoma Marker-CA153(CA153) ELISA Kit

NSL1741m 96 Test
EUR 528

Human Mammary Fibroblasts

ABC-TC3694 1 vial Ask for price
Description: Fibroblasts are the most common types of mammary stromal cells. Mammary stromal cells differentiate into fibroblasts, adipocytes or vascular structures in a hormone- and substatum-dependent manner, and may explain the dramatic changes in stromal composition during both normal mammary gland development and tumorigenesis. The interaction between stromal cells and tumor cells is known to play a major role in cancer growth and progression. The Mammary stromal fibroblasts express and produce cytokines such as SF witch plays roles in mammary cancer. HMF from Gentaur Research Laboratories are isolated from human mammary tissue. HMF are cryopreserved at primary culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HMF are characterized by immunofluorescent method with antibodies to fibronectin, CD90 and vimentin. HMF are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HMF are guaranteed to further expand for 15 population doublings at the conditions provided by Gentaur Research Laboratories.

Mammary Dissociation System 1 (Adipocytes), Mouse and Rat

4-20321 ea Ask for price

Mammary Dissociation System 2 (Epithelial), Mouse balb/c

4-20322 ea Ask for price

Mammary Dissociation System 4 (Epithelial, Swiss 3T3), Mouse

4-20324 ea Ask for price

Mouse mammary carcinoma marker CA15-3 (CA15-3) Elisa Kit

EK732216 96 Wells
EUR 0.86

Human Mammary Smooth Muscle

ABC-TC3697 1 vial Ask for price
Description: Human mammary smooth muscle, female, 49, bilateral breast lumps

Rat Mammary Epithelial Cells

ABC-TC4166 1 vial Ask for price
Description: Rat Mammary Epithelial Cells from Gentaur are isolated from tissue of 1-day-old neonatal laboratory Sprague–Dawley Rats. Rat Mammary Epithelial Cells are grown in T25 tissue culture flask pre-coated with gelatin-based coating solution for 0.5 hour and incubated in Gentaur's Cell Culture Medium for 3-5 days. Cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains 1x10^6 cells and is delivered frozen.Rat Mammary Epithelial Cells are characterized by immunofluorescent staining with antibodies of E-cadherin and ZO-1. Rat Mammary Epithelial Cells are negative for bacteria, yeast, fungi, and mycoplasma. Cells can be expanded for 3-7 passages at a split ratio of 1:2 or 1:3 under the cell culture conditions specified by Gentaur. Repeated freezing and thawing of cells is not recommended.Standard biochemical procedures performed with epithelial cell cultures include the assays of cell to cell adhesion and migration, RT-PCR, Western blotting, immunoprecipitation, immunofluorescent staining or immunofluorescent flow cytometry or generating cell derivatives for desired research applications.

Mammary Epithelial Medium Kit

TM043 1 Kit
EUR 300

Mouse Breast PrimaCell: Normal Mammary Epithelial Primary Cells

2-82021 1 Kit Ask for price

Mammary Dissociation System 5 (Epitheliall), Mouse primary tumor

4-20325 ea Ask for price

Mouse Mammary carcinoma Marker/Carbohydrate antigen15 3 ELISA kit

E03C0670-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Mammary carcinoma Marker/Carbohydrate antigen15 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mammary carcinoma Marker/Carbohydrate antigen15 3 ELISA kit

E03C0670-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Mammary carcinoma Marker/Carbohydrate antigen15 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mammary carcinoma Marker/Carbohydrate antigen15 3 ELISA kit

E03C0670-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Mammary carcinoma Marker/Carbohydrate antigen15 3 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Mammary carcinoma Marker/Carbohydrate antigen15 3 ELISA kit

E01A19829 96T
EUR 700
Description: ELISA

Rat mammary smooth muscle cells

ABC-TC4169 1 vial Ask for price
Description: Rat mammary smooth muscle cells, 8-week Wistar rat

Rat Mammary carcinoma Marker ELISA

E01A14589 96T
EUR 700
Description: ELISA

Immortalized Mouse Prolactin-Responsive Mammary Epithelial Cells (HC11)

T0672 1x106 cells / 1.0 ml Ask for price

Mouse mammary tumor virus receptor homolog 1 (MTVR1) polyclonal antibody

ABP-PAB-10111 100 ug Ask for price

Human Mammary Epithelial Cells, Male

ABC-TC3693 1 vial Ask for price
Description: Human Mammary Epithelial Cells, when grown in LIMam Medium, provide an ideal serum-free culture model for many areas of research. Common uses of HMEC include the study of breast cancer development, three dimensional culture and carcinogen screening.Cell Features:HMEC are cryopreserved as tertiary cells, e.g. cells are isolated from human mammary tissue and expanded three times in culture vessels before being harvested for cryopreservation.HMEC are extensively tested for quality and optimal performance.Gentaur guarantees performance and quality.

Goat Mammary carcinoma Marker ELISA

E01A49497 96T
EUR 700
Description: ELISA

Human Mammary Basal Epithelial Cells

ABC-TC3690 1 vial Ask for price
Description: human mammary basal epithelial cells are isolated from mammary tissue of healthy non-diabetic donors between 18 and 60 years old who have undergone elective surgery. The cells are isolated by digestion of the tissue to generate organoid structures.

Human Mammary Epithelial Cells, Adult

ABC-TC3691 1 vial Ask for price
Description: The mammary gland consists of pseudostratified epithelia, with myoepithelila cells resting upon a basement membrane and apical glandular epithelial cells facing the lumen of the ducts and alveoli. Mammary epithelial cells undergo changes in growth, invasion, and differentiation throughout much of adulthood, and most strikingly during pregnancy, lactation, and involution. They proliferate and invade the surrounding extracellular matrix during the fetal and postnatal development of the gland, and then more vigorously at puberty as the branches of the mammary epithelial tree are formed.HMEpiC from Gentaur Research Laboratories are isolated from normal human breast tissue. HMEpiC are cryopreserved at passage one culture and delivered frozen. Each vial contains 5×10^5 cells in 1 ml volume. HMEpiC are characterized by immunofluorescent method with cytokeratine antibodies. HMEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HMEpiC are guaranteed to further expand for 15 population doublings in the conditions provided by Gentaur Research Laboratories

Sheep Mammary carcinoma Marker ELISA

E01A101790 96T
EUR 700
Description: ELISA

Human Mammary carcinoma Marker ELISA

E01A5842 96T
EUR 700
Description: ELISA

Human Mammary Epithelial Cells, Female

ABC-TC3692 1 vial Ask for price
Description: Human Mammary Epithelial Cells, when grown in LIMam Medium, provide an ideal serum-free culture model for many areas of research. Common uses of HMEC include the stages of breast cancer development, three dimensional culture and carcinogen screening.Cell Features:HMEC are cryopreserved as tertiary cells, e.g. cells are isolated from human mammary tissue and expanded three times in culture vessels before being harvested for cryopreservation.HMEC are extensively tested for quality and optimal performance.Gentaur guarantees performance and quality.

Rabbit Mammary carcinoma Marker ELISA

E01A32063 96T
EUR 700
Description: ELISA

Monkey Mammary carcinoma Marker ELISA

E01A75644 96T
EUR 700
Description: ELISA

Bovine Mammary carcinoma Marker ELISA

E01A84363 96T
EUR 700
Description: ELISA

Canine Mammary carcinoma Marker ELISA

E01A66927 96T
EUR 700
Description: ELISA

Human Mammary Luminal Epithelial Cells

ABC-TC3695 1 vial Ask for price
Description: Human Mammary Luminal Epithelial Cell

Chicken Mammary carcinoma Marker ELISA

E01A93080 96T
EUR 700
Description: ELISA

Porcine Mammary carcinoma Marker ELISA

E01A58215 96T
EUR 700
Description: ELISA

Human Primary Mammary Epithelial Cells

T4036 5x10^5 cells / 1.0 ml
EUR 625

Pig Mammary carcinoma Marker ELISA kit

E07M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Mammary carcinoma Marker ELISA kit

E07M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Mammary carcinoma Marker ELISA kit

E07M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Mammary carcinoma Marker ELISA kit

E08M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Mammary carcinoma Marker ELISA kit

E08M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Mammary carcinoma Marker ELISA kit

E08M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Mammary carcinoma Marker ELISA kit

E02M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Mammary carcinoma Marker ELISA kit

E02M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Mammary carcinoma Marker ELISA kit

E02M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Mammary carcinoma Marker ELISA kit

E06M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Mammary carcinoma Marker ELISA kit

E06M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Mammary carcinoma Marker ELISA kit

E06M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Primary Mammary Smooth Muscle Cells

T4851 5x10^5 cells / 1.0 ml Ask for price

Mouse Breast PrimaCell: Normal Mammary Epithelial Primary Cells Growth Medium

9-32021 5 x 100 ml Ask for price

Immortalized Human Mammary Epithelial Cells

T0450 1x106 cells / 1.0 ml
EUR 1243.2

Human Mammary carcinoma Marker ELISA kit

E01M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Mammary carcinoma Marker ELISA kit

E01M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Mammary carcinoma Marker ELISA kit

E01M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Immortalized Human Mammary Fibroblasts (HMF3A)

T0153 1x106 cells / 1.0 ml Ask for price

Immortalized Human Mammary Fibroblasts (HMF3S)

T0154 1x106 cells / 1.0 ml Ask for price

Rabbit Mammary carcinoma Marker ELISA kit

E04M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Mammary carcinoma Marker ELISA kit

E04M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Mammary carcinoma Marker ELISA kit

E04M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Mammary carcinoma Marker ELISA kit

E09M0221-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Monkey Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Mammary carcinoma Marker ELISA kit

E09M0221-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Monkey Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Mammary carcinoma Marker ELISA kit

E09M0221-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Monkey Mammary carcinoma Marker in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Mammary carcinoma Marker ELISA

E01A40777 96T
EUR 700
Description: ELISA

Mouse Breast Tissue Preparation Buffer: Normal Mammary Epithelial Primary Cells

9-80135 1 x 100 ml Ask for price

Human Primary Mammary Epithelial Cells (HMEpC)

P0006038 One Frozen vial
EUR 600

mmu-miRNome MicroRNA Profiling Kit [Mouse]

RA670A-1 20 profiles
EUR 2046

Mammary Dissociation System 6 (Epithelial), Rat

4-20326 ea Ask for price

Expression plasmid for mouse microRNA Let7b

SC400709 10 µg Ask for price

Expression plasmid for mouse microRNA Let7d

SC400712 10 µg Ask for price

Expression plasmid for mouse microRNA Let7e

SC400713 10 µg Ask for price

Expression plasmid for mouse microRNA Let7g

SC400716 10 µg Ask for price

Expression plasmid for mouse microRNA Mir17

SC400798 10 µg Ask for price

Expression plasmid for mouse microRNA Mir21

SC400915 10 µg Ask for price

Expression plasmid for mouse microRNA Mir22

SC400928 10 µg Ask for price

Expression plasmid for mouse microRNA Mir25

SC400938 10 µg Ask for price

Expression plasmid for mouse microRNA Mir28

SC400944 10 µg Ask for price

Expression plasmid for mouse microRNA Mir31

SC400980 10 µg Ask for price

Expression plasmid for mouse microRNA Mir32

SC400981 10 µg Ask for price

Expression plasmid for mouse microRNA Mir33

SC400991 10 µg Ask for price

Expression plasmid for mouse microRNA Mir7b

SC401225 10 µg Ask for price

Expression plasmid for mouse microRNA Mir93

SC401248 10 µg Ask for price

Expression plasmid for mouse microRNA Mir96

SC401250 10 µg Ask for price

Expression plasmid for mouse microRNA Mir98

SC401251 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR21b

SC402469 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR21c

SC402470 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR28b

SC402472 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR28c

SC402473 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR30f

SC402523 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR432

SC402584 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR599

SC402659 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR664

SC402761 10 µg Ask for price

Expression Plasmid of Mouse microRNA MIR767

SC403043 10 µg Ask for price

Breast Tissue Slide (Invasive Mammary Carcinoma)

10-009-10um 10 um
EUR 241.8

Breast Tissue Slide (Invasive Mammary Carcinoma)

10-009-4um 4 um
EUR 216.6

Expression plasmid for mouse microRNA Mir100

SC400718 10 µg Ask for price

Expression plasmid for mouse microRNA Mir105

SC400723 10 µg Ask for price

Expression plasmid for mouse microRNA Mir107

SC400726 10 µg Ask for price

Expression plasmid for mouse microRNA Mir10a

SC400727 10 µg Ask for price

Expression plasmid for mouse microRNA Mir10b

SC400728 10 µg Ask for price

Expression plasmid for mouse microRNA Mir122

SC400744 10 µg Ask for price

Expression plasmid for mouse microRNA Mir126

SC400752 10 µg Ask for price

Expression plasmid for mouse microRNA Mir127

SC400753 10 µg Ask for price

Expression plasmid for mouse microRNA Mir132

SC400763 10 µg Ask for price

Expression plasmid for mouse microRNA Mir134

SC400767 10 µg Ask for price

Expression plasmid for mouse microRNA Mir136

SC400771 10 µg Ask for price

Expression plasmid for mouse microRNA Mir139

SC400775 10 µg Ask for price

Expression plasmid for mouse microRNA Mir140

SC400776 10 µg Ask for price

Expression plasmid for mouse microRNA Mir141

SC400777 10 µg Ask for price

Expression plasmid for mouse microRNA Mir142

SC400778 10 µg Ask for price

Expression plasmid for mouse microRNA Mir143

SC400779 10 µg Ask for price

Expression plasmid for mouse microRNA Mir144

SC400780 10 µg Ask for price

Expression plasmid for mouse microRNA Mir145

SC400781 10 µg Ask for price

Expression plasmid for mouse microRNA Mir147

SC400784 10 µg Ask for price

Expression plasmid for mouse microRNA Mir149

SC400787 10 µg Ask for price

Expression plasmid for mouse microRNA Mir150

SC400788 10 µg Ask for price

Expression plasmid for mouse microRNA Mir151

SC400789 10 µg Ask for price

Expression plasmid for mouse microRNA Mir152

SC400790 10 µg Ask for price

Expression plasmid for mouse microRNA Mir153

SC400791 10 µg Ask for price

Expression plasmid for mouse microRNA Mir154

SC400792 10 µg Ask for price

Expression plasmid for mouse microRNA Mir155

SC400793 10 µg Ask for price

Expression plasmid for mouse microRNA Mir15a

SC400794 10 µg Ask for price

Expression plasmid for mouse microRNA Mir15b

SC400795 10 µg Ask for price

Expression plasmid for mouse microRNA Mir183

SC400806 10 µg Ask for price

Expression plasmid for mouse microRNA Mir184

SC400808 10 µg Ask for price

Expression plasmid for mouse microRNA Mir185

SC400809 10 µg Ask for price

Expression plasmid for mouse microRNA Mir186

SC400810 10 µg Ask for price

Expression plasmid for mouse microRNA Mir187

SC400811 10 µg Ask for price

Expression plasmid for mouse microRNA Mir18a

SC400821 10 µg Ask for price

Expression plasmid for mouse microRNA Mir18b

SC400822 10 µg Ask for price

Hsa-miR-3613-5p identified as prognostic DE-miRNA. Functional enrichment analysis showed that the target gene HSA-miR-3613-5p may be related to p53 signaling pathway.

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