Extracellular Vesicle Proteins and MicroRNAs as Biomarkers for Traumatic Brain Injury

Extracellular Vesicle Proteins and MicroRNAs as Biomarkers for Traumatic Brain Injury

traumatic brain injury (TBI) is a heterogeneous condition, associated with diverse etiology, clinical presentation and severity, and can lead to chronic neurobehavioral sequelae. The rapidly growing field of TBI biomarkers to address many aspects of TBI pathology and improve clinical management. recent years have witnessed a marked increase in the number of publications and interest in the role of extracellular vesicles (EV), which includes exosomes, cell signaling, immune responses, and as a biomarker in a number of pathologies.

Exosomes have defined lipid bilayer well with surface marker that reflects the cell of origin and essence of water containing various biological materials including proteins (eg, cytokines and growth factors) and nucleic acids (eg, microRNAs). The presence of proteins associated with neurodegenerative changes such as amyloid-β, α-synuclein and tau phosphorylated at exosomes suggests a role in the initiation and propagation of nerve disease. However, the mechanism of cell communication in the brain involving exosomes and their role in pathology TBI are poorly understood. Exosomes promising biomarker TBI because they can pass through the blood-brain barrier and can be isolated from peripheral fluids, including serum, saliva, sweat, and urine.

Exosomal content is protected from enzymatic degradation by the exosome membrane and reflects the internal environment of the cell of origin, offer insight into the specific pathological process of tissue. The challenge in clinical use as a biomarker exosomal cargo including difficulty in isolating exosomes pure isolation process variable results, quantification of vesicles, and the lack of specificity markers exosomal.

In addition, there is no consensus on the nomenclature and characteristics of subtypes EV. In this review, we discuss the current technical limitations and challenges of using exosomes and other EVs as blood-based biomarkers, highlighting their potential as diagnostic and prognostic tool in TBI.

 Extracellular Vesicle Proteins and MicroRNAs as Biomarkers for Traumatic Brain Injury
Extracellular Vesicle Proteins and MicroRNAs as Biomarkers for Traumatic Brain Injury

MicroRNA-127-5p attenuates severe pneumonia with tumor necrosis factor receptor-associated factor 1

Pneumonia is a persistent and pervasive diseases, the effects of which can be severe. MicroRNA (mir) -127-5p has been used as a new biomarker for the diagnosis of severe pneumonia. This study aims to determine the function of miR-127-5p for severe pneumonia. An in vitro model of severe pneumonia in Ana-1 murine macrophages were established using lipopolysaccharide (LPS). Furthermore, reverse transcription-quantitative PCR and ELISA performed to detect mRNA and protein expression levels of interleukin (IL) -1β, IL-6 and tumor necrosis factor (TNF) -α. Western blotting was also performed to measure the activity of Akt and NF-kB.

The results showed that compared with the control group, LPS treatment increased by a factor 1 (TRAF1) associated TNF receptor expression levels and reduce the expression levels of miR-127-5p. Furthermore, the results revealed that the 3′-translated region of TRAF1 targeted by miR-127-5p. mir-127-5p rose mimic reduced LPS-induced IL-1β, IL-6 and TNF-α expression by targeting TRAF1, potentially mediated by inactivation of AKT and NF-kB signaling pathway.

Multiple stomach tumor with stomach tissue array

ST821 each
EUR 306
Description: Multiple stomach tumor with stomach tissue array, including pathology grade, TNM and clinical stage (reference AJCC 8th version), 80 cases/80 cores

Total RNA - Mouse Normal Tissue: Stomach

R1334248-50 50 ug
EUR 130

Multiple stomach cancer with stomach tissue array

ST2161b each
EUR 546
Description: Multiple stomach cancer with stomach tissue array, including pathology grade, TNM and clinical stage (reference AJCC 7th version), 216 cases/216 cores, replacing ST2161a

Genomic DNA - Mouse Normal Tissue: Stomach

D1334248 100 ug
EUR 286

Stomach Lysate

1415 0.1 mg
EUR 229.2
Description: Stomach tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Stomach Lysate

1475 0.1 mg
EUR 229.2
Description: Stomach tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Stomach cancer

ST1451a each
EUR 540
Description: Stomach cancer, matched NAT, matched metastasis tissue (recent year collection samples), including pathology grade, TNM and clinical stage, 71 cases/145 cores, replacing ST1451

Stomach tumor with stomach tissue test tissue array

T012b each
EUR 66
Description: Stomach tumor with stomach tissue test tissue array, including pathology grade, TNM and clinical stage, 12 cases/24 cores, replacing T012a

Stomach cancer (Lauren type) with stomach tissue array

ST2091a each
EUR 546
Description: Stomach cancer (Lauren type) with stomach tissue array, including pathology grade, TNM and clinical stage, 206 cases/208 cores, replacing ST2091

Stomach adenocarcinoma with matched stomach tissue array

ST781 each
EUR 270
Description: Stomach adenocarcinoma with matched stomach tissue array, including pathology grade, TNM and clinical stage, 26 cases/78 cores

Total Protein - Mouse Normal Tissue: Stomach

P1334248 1 mg
EUR 188

Mouse Stomach OptiTDS: Tissue Dissociation System

4-28202 1 Kit Ask for price

mmu-miRNome MicroRNA Profiling Kit [Mouse]

RA670A-1 20 profiles
EUR 2046

Rat Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells

2-82585 1 Kit Ask for price

Advanced stage of stomach cancer with stomach tissue array

ST963 each
EUR 306
Description: Advanced stage of stomach cancer with stomach tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition), 95 cases/95 cores,replaced by ST963a

Human Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells

2-96104 1 Kit Ask for price

Mouse Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Supplements with Serum (for 500 ml medium)

9-33088 1 Set Ask for price

Stomach disease spectrum (stomach cancer progression) tissue array

ST1001a each
EUR 306
Description: Stomach disease spectrum (stomach cancer progression) tissue array, including TNM, clinical stage and pathology grade, 100 cases/100 cores, replacing ST1001

Different stages of stomach cancer with stomach tissue array

ST8014 each
EUR 306
Description: Different stages of stomach cancer with stomach tissue array, including pathology grade, TNM and clinical stage, 80 cases/80 cores

cDNA - Lupus: stomach

C1236248Lup 40 reactions
EUR 737

Stomach cancer with matched adjacent normal stomach tissue array

ST244b each
EUR 78
Description: Stomach cancer with matched adjacent normal stomach tissue array, including pathology grade, TNM and clinical stage, 6cases/24cores, replacing ST244a

Advanced stage of stomach adenocarcinoma with stomach tissue array

ST963a each
EUR 306
Description: Advanced stage of stomach adenocarcinoma with stomach tissue array, including pathology grade, TNM and clinical stage, 95 cases/95 cores, replacing ST963

Fetal Stomach Lysate

XBL-10423 0.1 mg
EUR 500.1
Description: Fetal human stomach tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The fetal human stomach tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the stomach tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The stomach tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Stomach signet-ring cell carcinoma array with normal stomach tissue

ST881 each
EUR 306
Description: Stomach signet-ring cell carcinoma array with normal stomach tissue, including TNM and clinical stage, 88 cases/88 cores

Stomach Membrane Lysate

XBL-10924 0.1 mg
EUR 619.8
Description: Human stomach tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human stomach tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated stomach tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated stomach tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Human, Mouse, Rat - Stomach Tissue Array (5 slides/pk)

TAS-1013 1 pk
EUR 343.2

Stomach cancer tissue array with matched adjacent normal stomach tissue

ST801b each
EUR 270
Description: Stomach cancer tissue array with matched adjacent normal stomach tissue, including pathology grade, TNM and clinical stage, 40 cases/80 cores, replacing ST801a

Stomach-Pylorus Lysate

21-325 0.1 mg
EUR 468.6
Description: Monkey (Rhesus) stomach-pylorus tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The monkey (Rhesus) stomach-pylorus tissue total protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the stomach-pylorus tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The stomach-pylorus tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Rat Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Medium

9-25085 5 x 100 ml Ask for price

Human Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Medium

9-46104 5 x 100 ml Ask for price

Rat Stomach Tissue Preparation Buffer: Normal Stomach Mucosa Epithelial Cells

9-80292 1 x 100 ml Ask for price

Total RNA - Lupus: Stomach

R1236248Lup-50 50 ug
EUR 421.2

Human Stomach Tissue Preparation Buffer: Normal Stomach Mucosa Epithelial Cells

9-80104 1 x 100 ml Ask for price

MicroRNA Isolation Kit

KS341025 1 kit
EUR 247

Stomach Tissue Slide (Tumor)

10-827-10um 10 um
EUR 241.8

Stomach Tissue Slide (Tumor)

10-827-4um 4 um
EUR 216.6

Human Stomach Tumor lysate

HTL-1340 1 mg
EUR 927.6

Immortalized Mouse Stomach Epithelial Cells-Conditionally (ImSt)

T0569 1x106 cells / 1.0 ml Ask for price

Stomach Tissue Slide (Normal)

10-801-10um 10 um
EUR 241.8

Stomach Tissue Slide (Normal)

10-801-4um 4 um
EUR 216.6

Stomach Tissue Slide (Benign)

10-803-10um 10 um
EUR 241.8

Stomach Tissue Slide (Benign)

10-803-4um 4 um
EUR 216.6

Human Stomach Tissue Lysate

30R-AS039 150 ug
EUR 262.8
Description: Fresh tissue lysate isolated from human stomach

Normal stomach tissue array

BN01011b each
EUR 222
Description: Normal stomach tissue array, 24 cases/72 cores, replacing BN01011

Stomach cancer tissue array

BS01012e each
EUR 270
Description: Stomach cancer tissue array, including pathology grade, TNM and clinical stage (AJCC 7th edition), 72 cases/72 cores, replacing BS01012d

Stomach cancer tissue array

ST484d each
EUR 252
Description: Stomach cancer tissue array, including TNM and pathology grade and HER-2 result, 48 cases/48 cores

Stomach Lysate (0 Day Old)

1415-0 0.1 mg
EUR 229.2
Description: Stomach tissue lysate (0 Day Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Stomach Lysate (14 Day Old)

1415-14 0.1 mg
EUR 229.2
Description: Stomach tissue lysate (14 Day Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Stomach Lysate (7 Day Old)

1415-7 0.1 mg
EUR 229.2
Description: Stomach tissue lysate (7 Day Old) was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Stomach Tissue Lysate (Normal)

1717-01 0.1 mg
EUR 260.7
Description: Stomach tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 5% β-mercaptoethanol.

Stomach Tissue Slide (Abnormal)

10-826-10um 10 um
EUR 241.8

Stomach Tissue Slide (Abnormal)

10-826-4um 4 um
EUR 216.6

Stomach Membrane Tumor Lysate

XBL-10936 0.1 mg
EUR 752.1
Description: Human stomach tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human stomach tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated stomach tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated stomach tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Stomach Tissue Slide (Carcinoma)

10-814-10um 10 um
EUR 241.8

Stomach Tissue Slide (Carcinoma)

10-814-4um 4 um
EUR 216.6

Cancer MicroRNA qPCR Array

RA610A-1 10 profiles
EUR 1406.4

Cancer of the stomach, 102 cases (1.5mm)

STC1021 1
EUR 300
Description: Stomach cancer tissue array, 102 cases of normal/benign (5 cases) and cancer (97 cases with grading and TNM staging data) tissues

Cancer of the stomach, 228 cases (1.1mm)

STC2281 1
EUR 552
Description: Stomach cancer tissue array containing 8 cases of normal/benign conditions and 220 cases of cancers with grading and TNM staging data.

Stomach Diabetic Disease Lysate

XBL-10387 0.1 mg
EUR 796.2
Description: Human stomach tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human stomach tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the stomach tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The stomach tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Human microRNA-210(miR-210)ELISA

QY-E05678 96T
EUR 433.2

Mouse Normal Stomach (single section per slide) (5 slides/pack)

MoFPT066 5 slides
EUR 150

Stomach-Cardia Membrane Lysate

XBL-10939 0.1 mg
EUR 619.8
Description: Human stomach: Cardia tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human stomach: Cardia tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated stomach: Cardia tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated stomach: Cardia tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Stomach-Corpus Membrane Lysate

XBL-10942 0.1 mg
EUR 619.8
Description: Human stomach: corpus tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human stomach: corpus tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated stomach: corpus tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated stomach: corpus tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Stomach-Fundus Membrane Lysate

XBL-10945 0.1 mg
EUR 619.8
Description: Human stomach: fundus tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human stomach: fundus tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated stomach: fundus tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated stomach: fundus tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Stomach-Pylorus Membrane Lysate

XBL-10948 0.1 mg
EUR 619.8
Description: Human stomach: Pylorus tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human stomach: Pylorus tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated stomach: Pylorus tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated stomach: Pylorus tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

cDNA - Rat Normal Tissue: Stomach

C1434248 40 reactions
EUR 385

cDNA - Dog Normal Tissue: Stomach

C1734248 40 reactions
EUR 385

cDNA - Human Tumor Tissue: Stomach

C1235248 40 reactions
EUR 578

Rat Stomach Whole tissue lysate

RAL-1475 1 mg
EUR 628.8

Multiple stomach tumor with matched cancer adjacent or adjacent normal stomach tissue array

ST820 each
EUR 306
Description: Multiple stomach tumor with matched cancer adjacent or adjacent normal stomach tissue array, including pathology grade, TNM and clinical stage (reference AJCC 7th version), 40 cases/80 cores

Stomach Tissue Slide (Adenocarcinoma)

10-809-10um 10 um
EUR 241.8

Stomach Tissue Slide (Adenocarcinoma)

10-809-4um 4 um
EUR 216.6

Stomach adenocarcinoma tissue array

BS01011b each
EUR 270
Description: Stomach adenocarcinoma tissue array, including pathology grade, TNM and clinical stage, 72 cases/72 cores, replacing BS01011a

Stomach adenocarcinoma tissue array

ST1502 each
EUR 258
Description: Stomach adenocarcinoma tissue array, including TNM and pathology grade, 75 cases/150 cores

Stomach-Corpus Cytoplasmic Lysate

XBL-10941 0.1 mg
EUR 273.3
Description: Human stomach: corpus tissue cytoplasmic protein lysate was prepared by isolating the cytoplasmic protein from whole tissue homogenates using a proprietary technique. The human stomach: corpus tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The cytoplasmic protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, glycerol, and a cocktail of protease inhibitors. For quality control purposes, the isolated stomach: corpus tissue cytoplasmic protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated stomach: corpus tissue cytoplasmic protein is then Western analyzed by GAPDH antibody, and the expression level is consistent with each lot.

Mouse Stomach FibrOut: Fibroblast Inhibitory System (for 500 ml medium)

7-15181 1 Kit Ask for price

Stomach cancer tissue test array

T011b each
EUR 48
Description: Stomach cancer tissue test array, including pathology grade, TNM and clinical stage, 6 cases/24 cores, replacing T011a

Stomach cancer test tissue array

T014a each
EUR 48
Description: Stomach cancer test tissue array, including pathology grade, TNM and clinical stage, 6 cases/24 cores replacing T014

Epithelial Dissociation System 10 (Stomach epithelial), Mouse and Rat

4-20260 ea Ask for price

Total RNA - Diabetic Disease: Stomach

R1236248Dia-50 50 ug
EUR 421.2

MicroRNA scramble in CD511 - Virus

PMIRH000VA-1 1x10^6 IFUs
EUR 715

Stomach Tissue Slide (Malignant Tumor)

10-807-10um 10 um
EUR 241.8

Stomach Tissue Slide (Malignant Tumor)

10-807-4um 4 um
EUR 216.6

Stomach Tissue Slide (Malignant Tumor)

RF10002-05-10um 10 um
EUR 241.8

Stomach Tissue Slide (Malignant Tumor)

RF10002-05-4um 4 um
EUR 216.6

Total RNA - Rat Normal Tissue: Stomach

R1434248-50 50 ug
EUR 209

Stem Cell MicroRNA Profiling Panel

RA620A-1 10 profiles
EUR 1406.4

Mouse SeraMir Exosome RNA 384 microRNA qPCR Profiler Assay Set (20 assays)

RA811A-1 20 profiles
EUR 469

Microbiomaster Stomacher 80

MIX3002 EACH
EUR 4065.64

Total RNA - Human Tumor Tissue: Stomach

R1235248-50 50 ug
EUR 400

Genomic DNA - Rat Normal Tissue: Stomach

D1434248 100 ug
EUR 286

SanPrep Column microRNA Miniprep Kit

SK8811 50prep
EUR 151.32

cDNA - Human Adult Normal Tissue: Stomach

C1234248 40 reactions
EUR 385

Stomach cancer with normal tissue array

ST2083 each
EUR 546
Description: Stomach cancer with normal tissue array, including pathology grade, TNM and clinical stage, 69 cases/207 cores

Pepsin (3000 U/mg), Porcine Stomach Mucosa

PEP15-01 1 g
EUR 169.2

cDNA - Monkey (Rhesus) Normal Tissue: Stomach

C1534248 40 reactions
EUR 385

Total Protein - Human Tumor Tissue: Stomach

P1235248 1 mg
EUR 310

Rat Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Supplements with Serum (for 500 ml medium)

9-26085 1 Set Ask for price

Human Stomach PrimaCell: Normal Stomach Mucosa Epithelial Cells Growth Supplements with Serum (for 500 ml medium)

9-47104 1 Set Ask for price

96 Well Stomach Tumor Genomic DNA Plate

D8235248-1 1 plate
EUR 328

Matched Pair Tissue Slides - Stomach Tissue

10-800-MPPT 1 pack
EUR 241.8
Description: The Matched Pair Paraffin Tissue (MPPT) slides are designed for identifying tumor-specific/metastasis genes or proteins. Slices from normal and malignant tissues are mounted on each MPPT slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across normal and cancerous tissue.

Frozen Tissue Section - Human Tumor: Stomach

T1235248 5 slides
EUR 330

Stomach Tissue Slide (mucinous Adenocarcinoma)

10-810-10um 10 um
EUR 241.8

Stomach Tissue Slide (mucinous Adenocarcinoma)

10-810-4um 4 um
EUR 216.6

MicroRNA Precursor Pooled Plasmid Library

PMIRHPLPA-1 1 aliquot plasmid DNA
EUR 60

cDNA - Human Diabetic Diseased Tissue: Stomach

C1236248Dia 40 reactions
EUR 729

Membrane Protein - Human Tumor Tissue: Stomach

P3235248 0.1 mg
EUR 410

rno-miRNome MicroRNA Profiling Kit [Rat]

RA680B-1 20 complete profiles
EUR 2006.4

Human Cancer PrimaCell16: Stomach Tumor Cells

2-96039 1 Kit Ask for price

cDNA - Monkey (Cynomolgus) Normal Tissue: Stomach

C1534248-Cy 40 reactions
EUR 385

Multiple Species Tissue Slides - Stomach Tissue

10-800-MSTA 1 pack
EUR 241.8
Description: The Multiple Species Tissue Array (MSTA) slides were designed to study protein expression patterns in different cells and tissues from multiple species. Tissue slices from three different species are mounted on each MSTA slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across different species. MSTA slides can also be used to quickly determine the species reactivity of a given antibody.

Cancer of the stomach, 75 cases (1.1mm), set 1

STC1501 1
EUR 300
Description: Stomach cancer tissue array, set 1, non-overlapping with STC1502 or STC1503, 150 cores from normal/benign (5 cases) and cancer (70 cases with grading and TNM staging data) tissues in duplicates

Cancer of the stomach, 75 cases (1.1mm), set 2

STC1502 1
EUR 300
Description: Stomach cancer tissue array, set 2, non-overlapping with STC1501 or STC1503, 150 cores from normal/benign (5 cases) and cancer (70 cases with grading and TNM staging data) tissues in duplicates

Cancer of the stomach, 75 cases (1.1mm), set 3

STC1503 1
EUR 300
Description: Stomach cancer tissue array, set 3, non-overlapping with STC1501 or STC1502, 150 cores from normal/benign (5 cases) and cancer (70 cases with grading and TNM staging data) tissues in duplicates

FFPE Genomic DNA - Human Tumor Tissue: Stomach

D2235248 2 ug
EUR 960

Stomach cancer and lung cancer tissue array

SLC601 each
EUR 306
Description: Stomach cancer and lung cancer tissue array, including TNM and pathology grade, 60 cases/60 cores

Total RNA - Human Adult Normal Tissue: Stomach

R1234248-50 50 ug
EUR 170

hsa-miRNome MicroRNA Profiling Kit [Human]

RA660A-1 20 profiles
EUR 2212.8

Rat Stomach OptiTDS: Tissue Dissociation System

4-28292 1 Kit Ask for price

Stomach carcinoma for antibody screening array

ST1002 each
EUR 306
Description: Stomach carcinoma for antibody screening array, including TNM, clinical stage and pathology grade, 25 cases/100 cores

Common diseases of the stomach, 24 cases (2mm)

STD481 1
EUR 265.2
Description: Stomach disease tissue array, 48 cores, 24 cases of normal, inflammatory and neoplastic conditions of the stomach in duplicates

Stomach Tumor Tissue Array - Duplicated 70 cases covering all the common types of stomach cancer and 5 cases of normal

Z7020046 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Stomach Tumor Tissue Array - Duplicated 36 cases covering all the common types of stomach cancer and 12 cases of normal

Z7020048 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

cDNA - Human Adult Normal Tissue: Stomach: Cardia

C1234250-10 10 reactions
EUR 215

cDNA - Human Adult Normal Tissue: Stomach: Corpus

C1234251-10 10 reactions
EUR 215

cDNA - Human Adult Normal Tissue: Stomach: Fundus

C1234252-10 10 reactions
EUR 215

Total RNA - Monkey (Rhesus) Normal Tissue: Stomach

R1534248-50 50 ug
EUR 191

Human Stomach OptiTDS: Tissue Dissociation System

4-28104 1 Kit Ask for price

cDNA - Human Adult Normal Tissue: Stomach: Pylorus

C1234253-10 10 reactions
EUR 215

Monkey (Cyno.) Normal Stomach Whole tissue lysate

MCL-1210 1 mg
EUR 628.8

Human Adult Stomach (Normal) Whole tissue lysate

HAL-1319 1 mg
EUR 628.8

Different stage of stomach cancer tissue array

ST1921 each
EUR 474
Description: Different stage of stomach cancer tissue array, including pathology grade, TNM and clinical stage, 96 cases/192 cores

miRZip-1 anti-miR-1 microRNA construct

MZIP1-PA-1 Bacterial Streak
EUR 620

miRZip-7 anti-miR-7 microRNA construct

MZIP7-PA-1 Bacterial Streak
EUR 620

miRZip-9 anti-miR-9 microRNA construct

MZIP9-PA-1 Bacterial Streak
EUR 620

Human Stomach Tissue Slide (Tumor) (5 slides/pk)

HTS-10827 1 pk
EUR 343.2

Stomach Tumor Tissue Array - Duplicated 70 cases covering all the common types of stomach cancer and 5 cases of normal a

Z7020045 5 slides
EUR 1657.2
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

cDNA - Monkey (Rhesus) Normal Tissue: Stomach: Cardia

C1534250 40 reactions
EUR 578

cDNA - Monkey (Rhesus) Normal Tissue: Stomach: Corpus

C1534251 40 reactions
EUR 578

cDNA - Monkey (Rhesus) Normal Tissue: Stomach: Fundus

C1534252 40 reactions
EUR 578

Total Protein - Human Adult Normal Tissue: Stomach

P1234248 1 mg
EUR 188

Normal stomach tissue and duodenum tissue array

SIN241 each
EUR 198
Description: Normal stomach tissue and duodenum tissue array, 24 cases/ 24 cores

Stomach cancer and adjacent normal tissue array

ST8015 each
EUR 306
Description: Stomach cancer and adjacent normal tissue array, including TNM and pathology grade, 80 cases/80 cores

Genomic DNA - Lupus: Stomach, from a single donor

D1236248Lup 50 ug
EUR 504

Human Stomach Tissue Slide (Normal) (5 slides/pk)

HTS-10801 1 pk
EUR 343.2

Human Stomach Tissue Slide (Benign) (5 slides/pk)

HTS-10803 1 pk
EUR 343.2

cDNA - Monkey (Rhesus) Normal Tissue: Stomach: Pylorus

C1534253 40 reactions
EUR 578

Monkey (Rhesus) Normal Stomach Whole tissue lysate

MRL-1321 1 mg
EUR 628.8

Frozen Tissue Section - Human Adult Normal: Stomach

T1234248 5 slides
EUR 343

OncoMir pooled microRNA precursor virus library

PMIRHOPLVA-1 1 virus aliquot
EUR 1429.2

miRZip-16 anti-miR-16 microRNA construct

MZIP16-PA-1 Bacterial Streak
EUR 620

miRZip-17 anti-miR-17 microRNA construct

MZIP17-AA-1 Miniprep DNA
EUR 620

miRZip-17 anti-miR-17 microRNA construct

MZIP17-PA-1 Bacterial Streak
EUR 620

miRZip-21 anti-miR-21 microRNA construct

MZIP21-PA-1 Bacterial Streak
EUR 620

miRZip-22 anti-miR-22 microRNA construct

MZIP22-PA-1 Bacterial Streak
EUR 620

miRZip-24 anti-miR-24 microRNA construct

MZIP24-PA-1 Bacterial Streak
EUR 620

miRZip-25 anti-miR-25 microRNA construct

MZIP25-PA-1 Bacterial Streak
EUR 620

miRZip-31 anti-miR-31 microRNA construct

MZIP31-PA-1 Bacterial Streak
EUR 620

miRZip-32 anti-miR-32 microRNA construct

MZIP32-PA-1 Bacterial Streak
EUR 620

miRZip-93 anti-miR-93 microRNA construct

MZIP93-PA-1 Bacterial Streak
EUR 620

miRZip-95 anti-miR-95 microRNA construct

MZIP95-PA-1 Bacterial Streak
EUR 620

miRZip-96 anti-miR-96 microRNA construct

MZIP96-PA-1 Bacterial Streak
EUR 620

miRZip-98 anti-miR-98 microRNA construct

MZIP98-PA-1 Bacterial Streak
EUR 620

Total RNA - Monkey (Cynomolgus) Normal Tissue: Stomach

R1534248-Cy 50 ug
EUR 191

MicroRNA precursor pooled library, HT prepackaged

PMIRHPLVAHT-1 10 virus aliquots
EUR 9763

Human Stomach Tissue Slide (Abnormal) (5 slides/pk)

HTS-10826 1 pk
EUR 343.2

Membrane Protein - Human Adult Normal Tissue: Stomach

P3234248 0.1 mg
EUR 270

Stomach cancer tissue array for antibody screening

ST1003b each
EUR 306
Description: Stomach cancer tissue array for antibody screening, including TNM, clinical stage and pathology grade, 50 cases/100 cores, replacing ST1003a

Paraffin Tissue Section - Human Adult Normal: Stomach

T2234248 5 slides
EUR 185

miRZip-100 anti-miR-100 microRNA construct

MZIP100-PA-1 Bacterial Streak
EUR 620

miRZip-101 anti-miR-101 microRNA construct

MZIP101-PA-1 Bacterial Streak
EUR 620

miRZip-103 anti-miR-103 microRNA construct

MZIP103-PA-1 Bacterial Streak
EUR 620

miRZip-107 anti-miR-107 microRNA construct

MZIP107-PA-1 Bacterial Streak
EUR 620

miRZip-10a anti-miR-10a microRNA construct

MZIP10a-PA-1 Bacterial Streak
EUR 620

miRZip-10b anti-miR-10b microRNA construct

MZIP10b-PA-1 Bacterial Streak
EUR 620

miRZip-122 anti-miR-122 microRNA construct

MZIP122-PA-1 Bacterial Streak
EUR 620

miRZip-124 anti-miR-124 microRNA construct

MZIP124-PA-1 Bacterial Streak
EUR 620

miRZip-128 anti-miR-128 microRNA construct

MZIP128-PA-1 Bacterial Streak
EUR 620

miRZip-132 anti-miR-132 microRNA construct

MZIP132-PA-1 Bacterial Streak
EUR 620

miRZip-134 anti-miR-134 microRNA construct

MZIP134-PA-1 Bacterial Streak
EUR 620

miRZip-136 anti-miR-136 microRNA construct

MZIP136-PA-1 Bacterial Streak
EUR 620

miRZip-137 anti-miR-137 microRNA construct

MZIP137-PA-1 Bacterial Streak
EUR 620

Collectively, the results suggest that miR-127-5p may attenuate severe pneumonia by reducing the production of inflammatory cytokines LPS-induced, and disable the AKT and NF-kB signaling pathway by targeting TRAF1.

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