MicroRNAs and Risk Factors for Diabetic Nephropathy in Egyptian Children and Adolescents with Type 1 Diabetes

MicroRNAs and Risk Factors for Diabetic Nephropathy in Egyptian Children and Adolescents with Type 1 Diabetes

Objective: It is currently available markers for the early detection of diabetic nephropathy (DN), the leading cause of end stage renal disease, has several limitations. There is ample evidence from previous studies on the role of several circulating microRNAs (miRNAs) in the early development of DN. This study aims to describe the expression of miRNA-377, miRNA-93, miRNA-25, miRNA-216A, and miRNA-21 in a sample of type 1 diabetic children and adolescents to explore their relationship with DN and several indices of renal injury.
Patients and methods: Seventy type 1 diabetic patients with diabetes duration of 5 years or more, recruited from Children’s Hospital, Faculty of Medicine, Cairo University. Quantitative real-time reverse-transcription PCR (qRT-PCR) was used to measure the expression of the above mentioned miRNAs in serum and to assess its relationship with the DN, and the risk factors studied.


Results: There were significantly higher percentage of up-regulation of miRNA-377 and miRNA-93 (P = 0.03, 0.02, respectively) in addition to significant down-regulation of miRNA-25 (P = 0.01) in patients with DN than in patients without DN. In patients with DN, the expression of miR-216A were significantly negatively correlated with creatinine (r = -0.4, P = 0.04) and positively correlated with eGFR using creatinine (r = 0.5, P = 0.03). In the same group, the expression of miR-21 was positively correlated with urinary cystatin C (r = 0.6, P = 0.01) and negatively correlated with e-GFR using cystatin C (r = -0.6, P = 0, 01).

MiRNA-93 was associated with an increased risk (odds ratio = 15, 95% CI = 12.03 to 24.63, P = 0.01), whereas miRNA-25 was associated with a decreased risk of albuminuria (odds ratio = 0.15, 95 % CI = 0.08- 0.55; P = 0.03)


Conclusion: miRNA-377, miRNA-93, miRNA-216A, and miRNA-21 may be involved in the pathogenesis of DN, whereas miRNA-25 may have a reno-protective role. More studies are needed to document the value of these miRNAs as diagnostic biomarkers and therapeutic targets in DN.

 MicroRNAs and Risk Factors for Diabetic Nephropathy in Egyptian Children and Adolescents with Type 1 Diabetes
MicroRNAs and Risk Factors for Diabetic Nephropathy in Egyptian Children and Adolescents with Type 1 Diabetes

MicroRNA Profiling in Paired Left and Right Eye, Lung, and Normal Mice Testes

Extensive physiological and pathophysiological differences exist in paired organ systems. However, the molecular basis for this difference is unknown. We previously reported that miRNAs are differentially expressed (DEMs) on the left and right kidneys of normal mice.

Here, we identified Dems on the left and right eyes, lungs, and testes of normal mice via RNA sequencing. As a result, we identified 26 Dems in the eye, with 23 higher and 3 lower in the left eye compared to the right eye; 21 Dems in the lungs, with 15 higher and lower 6 in left lung compared to right lung; and 54 Dems in the testicles, with 6 higher and 48 lower in the left testicle than the right testis. ten microRNAs (miRNAs) are subsequently examined by quantitative PCR test, and seven of them were confirmed. In addition, correlation analysis was conducted between paired organ miRNA expression and miRNA expression of a variety of body fluids.

cDNA from Monkey (Rhesus) Normal Tissue: Testis

C1534260 40 reactions
EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Monkey (Cynomolgus) Normal Tissue: Testis

C1534260-Cy 40 reactions
EUR 540
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Monkey Cancer/testis antigen 47A(CT47A1) ELISA kit

E09C2138-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen 47A(CT47A1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 47A(CT47A1) ELISA kit

E09C2138-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen 47A(CT47A1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 47A(CT47A1) ELISA kit

E09C2138-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen 47A(CT47A1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 47B(CT47B1) ELISA kit

E09C2139-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen 47B(CT47B1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 47B(CT47B1) ELISA kit

E09C2139-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen 47B(CT47B1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 47B(CT47B1) ELISA kit

E09C2139-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen 47B(CT47B1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 1(CTAG1A) ELISA kit

E09C2140-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Cancer/testis antigen 1(CTAG1A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 1(CTAG1A) ELISA kit

E09C2140-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Cancer/testis antigen 1(CTAG1A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 1(CTAG1A) ELISA kit

E09C2140-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Cancer/testis antigen 1(CTAG1A) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 2(CTAG2) ELISA kit

E09C2141-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Cancer/testis antigen 2(CTAG2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 2(CTAG2) ELISA kit

E09C2141-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Cancer/testis antigen 2(CTAG2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen 2(CTAG2) ELISA kit

E09C2141-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Cancer/testis antigen 2(CTAG2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bromodomain testis specific protein(BRDT) ELISA kit

E09B0840-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Bromodomain testis specific protein(BRDT) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bromodomain testis specific protein(BRDT) ELISA kit

E09B0840-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Bromodomain testis specific protein(BRDT) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Bromodomain testis specific protein(BRDT) ELISA kit

E09B0840-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Bromodomain testis specific protein(BRDT) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse ; Testis

02-715 100ng
EUR 401
Description: The Mouse ; Testis is available in Europe and for worldwide shipping via Gentaur.

Testis Lysate

1416 0.1 mg
EUR 191
Description: Testis tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Testis Lysate

1476 0.1 mg
EUR 191
Description: Testis tissue lysate was prepared by homogenization in modified RIPA buffer (150 mM sodium chloride, 50 mM Tris-HCl, pH 7.4, 1 mM ethylenediaminetetraacetic acid, 1 mM phenylmethylsulfonyl fluoride, 1% Triton X-100, 1% sodium deoxycholic acid, 0.1% sodium dodecylsulfate, 5 μg/ml of aprotinin, 5 μg/ml of leupeptin. Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Testis Lysate

1313 0.1 mg
EUR 191
Description: Testis tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. Protein concentration was determined with Bio-Rad protein assay. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Monkey Testis expressed sequence 10 protein(TEX10) ELISA kit

E09T0680-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Testis expressed sequence 10 protein(TEX10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Testis expressed sequence 10 protein(TEX10) ELISA kit

E09T0680-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Testis expressed sequence 10 protein(TEX10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Testis expressed sequence 10 protein(TEX10) ELISA kit

E09T0680-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Testis expressed sequence 10 protein(TEX10) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Testis Membrane Lysate

XBL-10957 0.1 mg
EUR 516.5
Description: Human testis tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human testis tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated testis tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated testis tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Testis Tumor Lysate

1381 0.1 mg
EUR 254
Description: Testis tumor tissue lysate was prepared by homogenization in lysis buffer (10 mM HEPES pH7.9, 1.5 mM MgCl2, 10 mM KCl, 1 mM ethylenediaminetetraacetic acid, 10% glycerol, 1% NP-40, and a cocktail of protease inhibitors). Tissue and cell debris was removed by centrifugation. The product was boiled for 5 min in 1 x SDS sample buffer (50 mM Tris-HCl pH 6.8, 12.5% glycerol, 1% sodium dodecylsulfate, 0.01% bromophenol blue) containing 50 mM DTT.

Monkey Cancer/testis antigen family 45 member A1(CT45A1) ELISA kit

E09C2133-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A1(CT45A1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A1(CT45A1) ELISA kit

E09C2133-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A1(CT45A1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A1(CT45A1) ELISA kit

E09C2133-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A1(CT45A1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A2(CT45A2) ELISA kit

E09C2134-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A2(CT45A2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A2(CT45A2) ELISA kit

E09C2134-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A2(CT45A2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A2(CT45A2) ELISA kit

E09C2134-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A2(CT45A2) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A3(CT45A3) ELISA kit

E09C2135-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A3(CT45A3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A3(CT45A3) ELISA kit

E09C2135-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A3(CT45A3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A3(CT45A3) ELISA kit

E09C2135-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A3(CT45A3) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A5(CT45A5) ELISA kit

E09C2137-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A5(CT45A5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A5(CT45A5) ELISA kit

E09C2137-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A5(CT45A5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A5(CT45A5) ELISA kit

E09C2137-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A5(CT45A5) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Fetal and adult testis expressed transcript protein(FATE1) ELISA kit

E09F0361-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Fetal and adult testis expressed transcript protein(FATE1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Fetal and adult testis expressed transcript protein(FATE1) ELISA kit

E09F0361-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Fetal and adult testis expressed transcript protein(FATE1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Fetal and adult testis expressed transcript protein(FATE1) ELISA kit

E09F0361-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Fetal and adult testis expressed transcript protein(FATE1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Testis Tissue Lysate

LYSATE0005 200ug
EUR 150
Description: This cell lysate is prepared from rat testis tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Mouse Testis Tissue Lysate

LYSATE0014 200ug
EUR 150
Description: This cell lysate is prepared from mouse testis tissue using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Mouse Testis Nuclear Extract

X12009 500 µg Ask for price
Description: kits suitable for this type of research

Human Testis Tumor lysate

HTL-1381 1 mg
EUR 773

Testis Tissue Slide (Normal)

11-701-10um 10 um
EUR 201.5

Testis Tissue Slide (Normal)

11-701-4um 4 um
EUR 180.5

Testis Tissue Slide (Abnormal)

11-710-10um 10 um
EUR 201.5

Testis Tissue Slide (Abnormal)

11-710-4um 4 um
EUR 180.5

Testis Liver Cirrhosis Lysate

XBL-10389 0.1 mg
EUR 663.5
Description: Human testis tissue lysate was prepared by homogenization using a proprietary technique. The tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The human testis tissue total protein is provided in a buffer including HEPES (pH7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, Sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the testis tissue pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The testis tissue is then Western analyzed by either GAPDH or β-actin antibody, and the expression level is consistent with each lot.

Testis Membrane Tumor Lysate

XBL-10966 0.1 mg
EUR 626.75
Description: Human testis tissue membrane protein lysate was prepared by isolating the membrane protein from whole tissue homogenates using a proprietary technique. The human testis tissue was frozen in liquid nitrogen immediately after excision and then stored at -70°C. The membrane protein is provided in a buffer including HEPES (pH 7.9), MgCl2, KCl, EDTA, Sucrose, Glycerol, sodium deoxycholate, NP-40, and a cocktail of protease inhibitors. For quality control purposes, the isolated testis tissue membrane protein pattern on SDS-PAGE gel is shown to be consistent for each lot by visualization with coomassie blue staining. The isolated testis tissue membrane protein is then Western analyzed by either GAPDH or β-actin antibody to confirm there is no signal or very weak signal.

Monkey Cancer/testis antigen family 45 member A4/A6(CT45A4) ELISA kit

E09C2136-192T 192 tests
EUR 1270
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A4/A6(CT45A4) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A4/A6(CT45A4) ELISA kit

E09C2136-48 1 plate of 48 wells
EUR 520
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A4/A6(CT45A4) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Cancer/testis antigen family 45 member A4/A6(CT45A4) ELISA kit

E09C2136-96 1 plate of 96 wells
EUR 685
Description: A sandwich ELISA for quantitative measurement of Monkey Cancer/testis antigen family 45 member A4/A6(CT45A4) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Testis Tumor Tissue Array - 16 cases of testis tumors and 8 cases of non-tumor testis tissues.

Z7020096 5 slides
EUR 1381
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

MicroRNA Isolation Kit

KS341025 1 kit
EUR 256
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Testis Expressed 10 (TEX10) Antibody

20-abx116034
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Testis Expressed 11 (TEX11) Antibody

20-abx116035
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Testis Expressed 12 (TEX12) Antibody

20-abx116036
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Testis Expressed 13A (TEX13A) Antibody

20-abx116037
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Testis Expressed 14 (TEX14) Antibody

20-abx116038
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Testis Specific, 10 (TSGA10) Antibody

20-abx116039
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Testis Expressed 13A (TEX13A) Antibody

20-abx311757
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific 10 (TSGA10) Antibody

20-abx003819
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Recombinant Human Testis Derived Transcript

7-06631 2µg Ask for price

Recombinant Human Testis Derived Transcript

7-06632 10µg Ask for price

Recombinant Human Testis Derived Transcript

7-06633 1mg Ask for price

Testis Specific 10 (TSGA10) Antibody

abx145551-100ug 100 ug
EUR 391

Testis Expressed 12 (TEX12) Antibody

abx030409-400ul 400 ul
EUR 523

Testis Expressed 12 (TEX12) Antibody

abx030409-80l 80 µl
EUR 286

Testis Specific 10 (TSGA10) Antibody

abx031103-400ul 400 ul
EUR 523

Testis Specific 10 (TSGA10) Antibody

abx031103-80l 80 µl
EUR 286

Testis Expressed 11 (TEX11) Antibody

abx433354-200ul 200 ul
EUR 286

Testis Expressed 10 (TEX10) Antibody

abx238604-100ug 100 ug
EUR 509

Testis Expressed 101 (TEX101) Antibody

abx238605-100ug 100 ug
EUR 551

Testis Expressed 11 (TEX11) Antibody

abx238606-100ug 100 ug
EUR 509

Testis Expressed 12 (TEX12) Antibody

abx238607-100ug 100 ug
EUR 509

Testis Expressed 13A (TEX13A) Antibody

abx238608-100ug 100 ug
EUR 551

Testis Expressed 264 (TEX264) Antibody

abx238611-100ug 100 ug
EUR 509

Testis Expressed 38 (TEX38) Antibody

abx238613-100ug 100 ug
EUR 509

Testis Specific 10 (TSGA10) Antibody

abx239042-100ug 100 ug
EUR 509

Testis Specific 13 (TSGA13) Antibody

abx239043-100ug 100 ug
EUR 551

Testis Specific 13 (TSGA13) Antibody

20-abx302813
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific 10 (TSGA10) Antibody

20-abx302841
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rat Testis Whole tissue lysate

RAL-1476 1 mg
EUR 524

Mouse Testis Whole tissue lysate

MAL-1416 1 mg
EUR 524

Human Adult cDNA Tissue: Testis

HA-260 10 rxn
EUR 415

Cancer MicroRNA qPCR Array

RA610A-1 10 profiles
EUR 1172

Human Cancer/testis antigen 1 (CTAG1A)

1-CSB-YP006125HU
  • EUR 430.00
  • EUR 234.00
  • EUR 1508.00
  • EUR 642.00
  • EUR 1009.00
  • EUR 291.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Cancer/testis antigen 1(CTAG1A) expressed in Yeast

Human Cancer/testis antigen 2 (CTAG2)

1-CSB-YP006127HUa4
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Cancer/testis antigen 2(CTAG2) expressed in Yeast

Recombinant Cancer/Testis Antigen 1B (CTAG1B)

4-RPJ316Hu01
  • EUR 490.66
  • EUR 234.00
  • EUR 1564.96
  • EUR 588.32
  • EUR 1076.64
  • EUR 391.00
  • EUR 3762.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Cancer/Testis Antigen 1B expressed in: E.coli

Recombinant Testis Anion Transporter 1 (TAT1)

4-RPE478Hu01
  • EUR 494.24
  • EUR 235.00
  • EUR 1578.40
  • EUR 592.80
  • EUR 1085.60
  • EUR 394.00
  • EUR 3796.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Testis Anion Transporter 1 expressed in: E.coli

Recombinant Testis Specific Kinase 1 (TESK1)

4-RPC789Hu01
  • EUR 472.74
  • EUR 229.00
  • EUR 1497.76
  • EUR 565.92
  • EUR 1031.84
  • EUR 379.00
  • EUR 3594.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Testis Specific Kinase 1 expressed in: E.coli

Recombinant Testis Specific Kinase 1 (TESK1)

4-RPC789Mu01
  • EUR 499.62
  • EUR 236.00
  • EUR 1598.56
  • EUR 599.52
  • EUR 1099.04
  • EUR 397.00
  • EUR 3846.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Testis Specific Kinase 1 expressed in: E.coli

Human Cancer/testis antigen 1 (CTAG1A)

1-CSB-EP006125HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Cancer/testis antigen 1(CTAG1A) expressed in E.coli

Human Cancer/testis antigen 2 (CTAG2)

1-CSB-EP006127HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Cancer/testis antigen 2(CTAG2) expressed in E.coli

Testis Derived Transcript Human Recombinant Protein

PROTQ9UGI8 Regular: 10ug
EUR 317
Description: TES Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 441amino acids (1-421 a.a.) and having a molecular mass of 50.1 kDa. The TES protein is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Cancer/Testis Antigen 1A (CTAG1A) Antibody

20-abx126874
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Cancer/Testis Antigen 1B (CTAG1B) Antibody

20-abx128209
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Testis Anion Transporter 1 (TAT1) Antibody

20-abx129200
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Testis Specific Kinase 1 (TESK1) Antibody

20-abx130977
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Testis Specific Kinase 1 (TESK1) Antibody

20-abx130978
  • EUR 425.00
  • EUR 133.00
  • EUR 1205.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Testis-expressed sequence 12 protein Antibody

20-abx110259
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Phosphorylase Kinase, gamma 2 (Testis) Antibody

20-abx114507
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Cancer/Testis Antigen 1A (CTAG1A) Antibody

20-abx111352
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Human Testis PrimaCell: Normal Sertoli Cells

2-96105 1 Kit Ask for price

Testis Specific 13 (TSGA13) Antibody (HRP)

20-abx309618
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific 13 (TSGA13) Antibody (FITC)

20-abx309619
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific 13 (TSGA13) Antibody (Biotin)

20-abx309620
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific 10 (TSGA10) Antibody (HRP)

20-abx310740
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific 10 (TSGA10) Antibody (FITC)

20-abx310741
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific 10 (TSGA10) Antibody (Biotin)

20-abx310742
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Expressed 13A (TEX13A) Antibody (HRP)

20-abx311758
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Expressed 13A (TEX13A) Antibody (FITC)

20-abx311759
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Expressed 13A (TEX13A) Antibody (Biotin)

20-abx311760
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cancer/Testis Antigen 5.1 (SSX1) Antibody

20-abx323587
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Testis-Expressed Protein 35 (Tex35) Antibody

20-abx307697
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Human Testis OptiTDS: Tissue Dissociation System

4-28105 1 Kit Ask for price

Cancer/Testis Antigen 5.1 (SSX1) Antibody

abx145140-100ug 100 ug
EUR 391

Cancer/testis Antigen 2 (CTAG2) Antibody

20-abx149592
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Cancer/Testis Antigen 1B (CTAG1B) Antibody

20-abx135754
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Testis Specific Kinase 1 (TESK1) Antibody

20-abx008652
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Bromodomain Testis-Specific Protein (BRDT) Antibody

abx025117-400ul 400 ul
EUR 523

Bromodomain Testis-Specific Protein (BRDT) Antibody

abx025117-80l 80 µl
EUR 286

Testis-Expressed Protein 9 (TEX9) Antibody

abx025800-400ul 400 ul
EUR 523

Testis-Expressed Protein 9 (TEX9) Antibody

abx025800-80l 80 µl
EUR 286

Testis-Expressed Protein 13B (TEX13B) Antibody

abx025974-400ul 400 ul
EUR 523

Testis-Expressed Protein 13B (TEX13B) Antibody

abx025974-80l 80 µl
EUR 286

Testis Serine Protease 1 (TESSP1) Antibody

abx026869-400ul 400 ul
EUR 523

Testis Serine Protease 1 (TESSP1) Antibody

abx026869-80l 80 µl
EUR 286

Cancer/Testis Antigen 1A (CTAG1A) Antibody

abx027441-400ul 400 ul
EUR 523

Cancer/Testis Antigen 1A (CTAG1A) Antibody

abx027441-80l 80 µl
EUR 286

Testis-Expressed Protein 33 (EAN57) Antibody

abx029059-400ul 400 ul
EUR 523

Testis-Expressed Protein 33 (EAN57) Antibody

abx029059-80l 80 µl
EUR 286

Testis Specific Kinase 1 (TESK1) Antibody

abx029069-400ul 400 ul
EUR 523

Testis Specific Kinase 1 (TESK1) Antibody

abx029069-80l 80 µl
EUR 286

Testis-Expressed Protein 2 (TEX2) Antibody

abx029879-400ul 400 ul
EUR 523

Testis-Expressed Protein 2 (TEX2) Antibody

abx029879-80l 80 µl
EUR 286

Cancer/testis Antigen 2 (CTAG2) Antibody

abx027593-400ul 400 ul
EUR 523

Cancer/testis Antigen 2 (CTAG2) Antibody

abx027593-80l 80 µl
EUR 286

Cancer/Testis Antigen 5.1 (SSX1) Antibody

abx238257-100ug 100 ug
EUR 551

Testis Anion Transporter 1 (TAT1) Antibody

20-abx174745
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Cancer/Testis Antigen 1B (CTAG1B) Antibody

20-abx171540
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug

Testis-Expressed Protein 43 (TEX43) Antibody

20-abx301458
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cancer/Testis Antigen 5.1 (SSX1) Antibody

20-abx302290
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Testis Specific Kinase 1 (TESK1) Antibody

abx331203-100ul 100 ul
EUR 425

Cancer/Testis Antigen 1A (CTAG1A) Antibody

abx331930-100ul 100 ul
EUR 425

Testis Specific Kinase 1 (TESK1) Antibody

20-abx327884
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Hyaluronidase (~300 U/mg: bovine testis)

RP-1469 1500 IU
EUR 164

Hyaluronidase (1000 U/mg), Ovine Testis

MPF-02 1 mU
EUR 590

Hyaluronidase (300 U/mg), Ovine Testis

HYO-01 10 g
EUR 651

Hyaluronidase (5000 U/mg), Ovine Testis

HYO-03 20 KU
EUR 408

cDNA from Mouse Normal Tissue: Testis

C1334260 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Rat Normal Tissue: Testis

C1434260 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

cDNA from Dog Normal Tissue: Testis

C1734260 40 reactions
EUR 376
Description: Can be used for various studies in the realm of gene expression, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total Protein from Liver Cirrhosis: Testis

P1236260Lcs 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Frozen Tissue Section - Human Tumor: Testis

T1235260 5 slides
EUR 338
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Paraffin Tissue Section - Human Testis Tumor

T2235260 5 slides
EUR 257
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Multiple Species Tissue Slides - Testis Tissue

11-700-MSTA 1 pack
EUR 201.5
Description: The Multiple Species Tissue Array (MSTA) slides were designed to study protein expression patterns in different cells and tissues from multiple species. Tissue slices from three different species are mounted on each MSTA slide which can then be treated as a single histological slide for H&E staining, immunohistochemistry, or in situ hybridization. This format allows a rapid analysis of protein expression and localization across different species. MSTA slides can also be used to quickly determine the species reactivity of a given antibody.

SanPrep Column microRNA Miniprep Kit

SK8811 50prep
EUR 126.1

MicroRNA scramble in CD511 - Virus

PMIRH000VA-1 1x10^6 IFUs
EUR 781

MicroRNA Precursor Pooled Plasmid Library

PMIRHPLPA-1 1 aliquot plasmid DNA
EUR 50

Finally, we explore the function and tissue Dems and conducted biological processes and target gene pathway enrichment analysis for Dems, providing insights into the physiological and pathophysiological differences between the two entities are paired organs. The article “Knockdown of microRNA-181a inhibits osteosarcoma cell growth and invasion through pyroptosis NLRP3-dependent triggering, by B.-G. Tian, ​​Z. Hua, Z.-J. Wang, J. Li, published in Eur Rev Med Pharmacol Sci 2020 have been drawn from the author. Publisher apologizes for any inconvenience this may cause.

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